Increased incidence of leukemia in patients with obstructive sleep apnea: Results from the national insurance claim data 2007-2014
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Eun Jung | - |
dc.contributor.author | Do Han, Kyung | - |
dc.contributor.author | Kim, Sung-Yong | - |
dc.contributor.author | Suh, Jeffrey D. | - |
dc.contributor.author | Kim, Jin Kook | - |
dc.contributor.author | Cho, Jae Hoon | - |
dc.date.accessioned | 2023-03-24T08:40:09Z | - |
dc.date.available | 2023-03-24T08:40:09Z | - |
dc.date.created | 2023-02-27 | - |
dc.date.issued | 2022-08 | - |
dc.identifier.issn | 1389-9457 | - |
dc.identifier.uri | http://scholarworks.bwise.kr/ssu/handle/2018.sw.ssu/43587 | - |
dc.description.abstract | Purpose: Prior research suggests a link between obstructive sleep apnea (OSA) and the likelihood of developing a variety of solid tumors; however, there are no studies assessing OSA and leukemia. This study is the first to identify a potential association between OSA and leukemia using data from the Korea National Health Insurance Service database. Methods: A total of 162,646 patients (>= 20 years of age and without any cancer history) newly diagnosed with OSA between 2011 and 2017 were included. A control group of 813,230 subjects was selected using propensity score matching based on age and sex. The mean follow-up time was 4.4 +/- 2.0 years. The primary endpoint was newly diagnosed leukemia of any type. The leukemia hazard ratio (95% confidence interval [CI]) was calculated for patients with OSA and compared with that of patients in the control group. Results: The incidence of leukemia among patients with OSA was significantly higher than that in the controls (1.35 [1.05-1.74]). The hazard ratio was the highest, 1.74 in those under 40 years, and gradually decreased with age, to 1.38 in those aged 40-65 years and 0.96 in those over 65. In particular, the incidence of lymphoid leukemia (2.06 [1.18-3.60]) was higher than that of myeloid (1.34 [1.00-1.81]) or unspecified leukemia (0.60 [0.20-1.58]). Conclusion: OSA is associated with an increased incidence of leukemia, particularly in patients younger than 40 years of age. (C) 2022 Elsevier B.V. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER | - |
dc.relation.isPartOf | SLEEP MEDICINE | - |
dc.title | Increased incidence of leukemia in patients with obstructive sleep apnea: Results from the national insurance claim data 2007-2014 | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.sleep.2022.05.009 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | SLEEP MEDICINE, v.96, pp.113 - 118 | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000833416100001 | - |
dc.identifier.scopusid | 2-s2.0-85130885407 | - |
dc.citation.endPage | 118 | - |
dc.citation.startPage | 113 | - |
dc.citation.title | SLEEP MEDICINE | - |
dc.citation.volume | 96 | - |
dc.contributor.affiliatedAuthor | Do Han, Kyung | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.subject.keywordAuthor | Obstructive sleep apnea | - |
dc.subject.keywordAuthor | Leukemia | - |
dc.subject.keywordAuthor | Lymphoid type | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | HYPOXIA | - |
dc.subject.keywordPlus | UVULOPALATOPHARYNGOPLASTY | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | GROWTH | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
Soongsil University Library 369 Sangdo-Ro, Dongjak-Gu, Seoul, Korea (06978)02-820-0733
COPYRIGHT ⓒ SOONGSIL UNIVERSITY, ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.