Risk of cancer in patients with insomnia: Nationwide retrospective cohort study (2009-2018)
DC Field | Value | Language |
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dc.contributor.author | Yoon, Kichul | - |
dc.contributor.author | Shin, Cheol Min | - |
dc.contributor.author | Han, Kyungdo | - |
dc.contributor.author | Jung, Jin Hyung | - |
dc.contributor.author | Jin, Eun Hyo | - |
dc.contributor.author | Lim, Joo Hyun | - |
dc.contributor.author | Kang, Seung Joo | - |
dc.contributor.author | Choi, Yoon Jin | - |
dc.contributor.author | Lee, Dong Ho | - |
dc.date.accessioned | 2023-07-11T05:40:05Z | - |
dc.date.available | 2023-07-11T05:40:05Z | - |
dc.date.created | 2023-07-04 | - |
dc.date.issued | 2023-04 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | http://scholarworks.bwise.kr/ssu/handle/2018.sw.ssu/44095 | - |
dc.description.abstract | PurposeTo investigate the association between insomnia and the risk of various cancers using the Korean National Health Insurance Service database. Materials and methodsPatients who underwent a national health examination in 2009 were followed-up until 2018. Newly-diagnosed cancers were collected one year after the baseline. Insomnia was defined as having a diagnosis of F510 or G470 within one year prior to enrollment. The incidence of various cancers was compared between patients with and without insomnia. ResultsIn the overall study population (N = 3,982,012), the risk for any type of cancer was not different between controls and insomnia patients (adjusted hazard ratio [aHR]: 0.990). However, it was different by age; insomnia increased the risk of any cancer in younger age groups (20-39y and 40-59y, aHR:1.310 and 1.139, respectively) but it significantly decreased the risk in the 60-79y age group (aHR: 0.939). In cancer type, colorectal cancer risk was lower (aHR: 0.872, P < 0.0001), whereas leukemia risk was higher (aHR: 1.402, P < 0.0001) in patients with insomnia than in those without it, regardless of sex. In men, the risk of stomach cancer was lower (aHR: 0.882, P = 0.0003), and the risks of lung (aHR:1.114, P = 0.0005), kidney (aHR 1.226, P = 0.0107), and prostate (aHR:1.101, P = 0.0028) cancers were higher in insomnia patients than in control patients. In women, insomnia patients compared to control patients showed a lower risk of ovarian cancer (aHR:0.856, P = 0.0344, respectively), while they had a higher risk of oral (aHR:1.616, P = 0.002), thyroid (aHR:1.072, P = 0.0192), and nerve (aHR: 1.251, P = 0.016) cancers. ConclusionInsomnia is associated with an increased or decreased risk of some cancers, depending on age, cancer type and sex. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | PUBLIC LIBRARY SCIENCE | - |
dc.relation.isPartOf | PLOS ONE | - |
dc.title | Risk of cancer in patients with insomnia: Nationwide retrospective cohort study (2009-2018) | - |
dc.type | Article | - |
dc.identifier.doi | 10.1371/journal.pone.0284494 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | PLOS ONE, v.18, no.4 | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000990750100062 | - |
dc.identifier.scopusid | 2-s2.0-85153542683 | - |
dc.citation.number | 4 | - |
dc.citation.title | PLOS ONE | - |
dc.citation.volume | 18 | - |
dc.contributor.affiliatedAuthor | Han, Kyungdo | - |
dc.identifier.url | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0284494 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.subject.keywordPlus | OVARIAN-CANCER | - |
dc.subject.keywordPlus | SLEEP-APNEA | - |
dc.subject.keywordPlus | EPIDEMIOLOGY | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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