Detailed Information
Cited 0 time in 
Cited 8 time in 
Cited 8 time in
Metadata Downloads
Inhibition of aldose reductase on rat lens by tartary buckwheatInhibition of Aldose Reductase on Rat Lens by Tartary Buckwheat
- Authors
- Mok, S.-Y.; Lee, J.M.; Kim, H.M.; Lee, D.G.; Yoon, Y.-H.; Cho, E.J.; Lee, S.
- Issue Date
- 2011
- Publisher
- 한국생약학회
- Keywords
- Aldose reductase; Diabetic complications; Rutin; Tartary buckwheat
- Citation
- Natural Product Sciences, v.17, no.3, pp 230 - 233
- Pages
- 4
- Journal Title
- Natural Product Sciences
- Volume
- 17
- Number
- 3
- Start Page
- 230
- End Page
- 233
- ISSN
- 1226-3907
- Abstract
- To evaluate the potential of naturally occurring aldose reductase (AR) inhibitors from food material, MeOH extract and stepwise polarity fractions from tartary buckwheat and two common Korean buckwheat cultivars, yangjul-maemil and daesan-maemil, were tested on AR inhibition in rat lens in vitro. The EtOAc fraction from tartary buckwheat exhibited good AR inhibitory activity (IC 50 value, 8.19 μg/ml). A portion of the EtOAc fraction from tartary buckwheat led to the isolation of rutin by MeOH recrystalization. Rutin exhibited good AR inhibitory activity (IC 50 value, 9.28 μM). These results suggest that tartary buckwheat could be a useful food material in the development of a novel AR inhibitory agent against diabetic complications.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Biotechnology & Natural Resource > ETC > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.