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Inhibition of aldose reductase from rat lenses by methanol extracts from Korean folk plantsInhibition of Aldose Reductase from Rat Lenses by Methanol Extracts from Korean Folk Plants
- Authors
- Kim, H.M.; Mok, S.-Y.; Lee, J.M.; Cho, E.J.; Choi, K.; Ku, J.; Park, K.-W.; Lee, S.
- Issue Date
- 2010
- Publisher
- 한국생약학회
- Keywords
- Diabetic complications; Korean folk plant; Rat lens aldose reductase
- Citation
- Natural Product Sciences, v.16, no.4, pp 285 - 290
- Pages
- 6
- Journal Title
- Natural Product Sciences
- Volume
- 16
- Number
- 4
- Start Page
- 285
- End Page
- 290
- ISSN
- 1226-3907
- Abstract
- The inhibition of rat lens aldose reductase (AR) in vitro using methanol extracts from Korean folk plants was investigated. Among them, the extracts of Saussurea grandifolia and Rumex crispus showed highest inhibition of AR. IC50 values of the extracts from S. grandifolia and R. crispus were demonstrated 0.07 and 0.05 mg/ml, respectively. Korean folk plants such as S. grandifolia and R. crispus has a possibility of new natural resources for the inhibition of AR.
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Collections - College of Biotechnology & Natural Resource > ETC > 1. Journal Articles
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