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Ginsenoside Rg12, a new dammarane-type triterpene saponin from Panax ginseng root

Authors
Lee, Dong GuLee, JaeminCho, Ik-HyunKim, Hak-JaeLee, Sang-WonKim, Young-OckPark, Chun-GunLee, Sang Hyun
Issue Date
Oct-2017
Publisher
KOREAN SOC GINSENG
Keywords
dammarane-type triterpene saponin; ginsenoside Rg12; Panax ginseng; white ginseng
Citation
JOURNAL OF GINSENG RESEARCH, v.41, no.4, pp 531 - 533
Pages
3
Journal Title
JOURNAL OF GINSENG RESEARCH
Volume
41
Number
4
Start Page
531
End Page
533
URI
https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/3845
DOI
10.1016/j.jgr.2016.10.002
ISSN
1226-8453
2093-4947
Abstract
Background: Panax ginseng has been used as Korean medicine for various diseases. It has antioxidant, hypotensive, sedative, analgesic, and endocrine activities. Dammarane-type triterpenes from the plant have various beneficial effects. Methods: A dammarane-type triterpene saponin was isolated from P. ginseng root through chromatography such as repeated column chromatography and medium pressure liquid chromatography. Results and conclusion: New dammarane-type triterpene saponin was isolated for the first time from nature. The structure was elucidated as ginsenoside Rg12 (1) based on spectral data. There may be good materials from P. ginseng for the development of industrial applications such as nutraceutical, pharmaceutical, and cosmeceutical purposes. (C) 2016 The Korean Society of Ginseng, Published by Elsevier Korea LLC.
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Lee, Sanghyun
대학원 (식물생명공학과)
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