Ginsenoside Rg12, a new dammarane-type triterpene saponin from Panax ginseng root
- Authors
- Lee, Dong Gu; Lee, Jaemin; Cho, Ik-Hyun; Kim, Hak-Jae; Lee, Sang-Won; Kim, Young-Ock; Park, Chun-Gun; Lee, Sang Hyun
- Issue Date
- Oct-2017
- Publisher
- KOREAN SOC GINSENG
- Keywords
- dammarane-type triterpene saponin; ginsenoside Rg12; Panax ginseng; white ginseng
- Citation
- JOURNAL OF GINSENG RESEARCH, v.41, no.4, pp 531 - 533
- Pages
- 3
- Journal Title
- JOURNAL OF GINSENG RESEARCH
- Volume
- 41
- Number
- 4
- Start Page
- 531
- End Page
- 533
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/3845
- DOI
- 10.1016/j.jgr.2016.10.002
- ISSN
- 1226-8453
2093-4947
- Abstract
- Background: Panax ginseng has been used as Korean medicine for various diseases. It has antioxidant, hypotensive, sedative, analgesic, and endocrine activities. Dammarane-type triterpenes from the plant have various beneficial effects. Methods: A dammarane-type triterpene saponin was isolated from P. ginseng root through chromatography such as repeated column chromatography and medium pressure liquid chromatography. Results and conclusion: New dammarane-type triterpene saponin was isolated for the first time from nature. The structure was elucidated as ginsenoside Rg12 (1) based on spectral data. There may be good materials from P. ginseng for the development of industrial applications such as nutraceutical, pharmaceutical, and cosmeceutical purposes. (C) 2016 The Korean Society of Ginseng, Published by Elsevier Korea LLC.
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