Is two-stage reimplantation effective for virulent pathogenic infection in a periprosthetic hip? A retrospective analysis
DC Field | Value | Language |
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dc.contributor.author | Yoon, Yong-Cheol | - |
dc.contributor.author | Lakhotia, Devendra | - |
dc.contributor.author | Oh, Jong-Keon | - |
dc.contributor.author | Moon, Jun Gyu | - |
dc.contributor.author | Prashant, Kumar | - |
dc.contributor.author | Shon, Won Yong | - |
dc.date.available | 2020-02-28T07:44:31Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2015-10-18 | - |
dc.identifier.issn | 2218-5836 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/10029 | - |
dc.description.abstract | AIM: To investigate the effectiveness of two-stage reimplantation using antibiotic-loaded bone cement (ALBC) and the risk factors associated with failure to control periprosthetic joint infection (PJI). METHODS: We retrospectively reviewed 38 consecutive hips managed using two-stage reimplantation with ALBC. The mean follow-up period was 5.4 years (range: 2.5-9 years). RESULTS: The causative pathogens were isolated from 29 patients (76%), 26 of whom were infected with highly virulent organisms. Sixteen patients (42%) underwent at least two first-stage debridements. An increased debridement frequency correlated significantly with high comorbidity (P < 0.001), a lower preoperative Harris hip score (HHS; P < 0.001), antimicrobial resistance, and gram-negative and polymicrobial infection (P = 0.002). Of the 35 patients who underwent two-stage reimplantation, 34 showed no signs of recurrence of infection. The mean HHS improved from 46 +/- 12.64 to 78 +/- 10.55 points, with 7 (20%), 12 (34%), 11 (32%) and 5 (14%) patients receiving excellent, good, fair and poor ratings, respectively. CONCLUSION: The current study demonstrated that two-stage reimplantation could successfully treat PJI after hip arthroplasty. However, the ability of ALBC to eradicate infection was limited because frequent debridement was required in high-risk patients (i.e., patients who are either in poor general health due to associated comorbidities or harbor infections due to highly virulent, difficult-to-treat organisms). Level of evidence: Level IV. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | BAISHIDENG PUBLISHING GROUP INC | - |
dc.relation.isPartOf | WORLD JOURNAL OF ORTHOPEDICS | - |
dc.title | Is two-stage reimplantation effective for virulent pathogenic infection in a periprosthetic hip? A retrospective analysis | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000439316800007 | - |
dc.identifier.doi | 10.5312/wjo.v6.i9.712 | - |
dc.identifier.bibliographicCitation | WORLD JOURNAL OF ORTHOPEDICS, v.6, no.9, pp.712 - 718 | - |
dc.identifier.scopusid | 2-s2.0-84944608211 | - |
dc.citation.endPage | 718 | - |
dc.citation.startPage | 712 | - |
dc.citation.title | WORLD JOURNAL OF ORTHOPEDICS | - |
dc.citation.volume | 6 | - |
dc.citation.number | 9 | - |
dc.contributor.affiliatedAuthor | Yoon, Yong-Cheol | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Two-stage reimplantation | - |
dc.subject.keywordAuthor | Periprosthetic infection | - |
dc.subject.keywordAuthor | Antibiotic-loaded bone cement | - |
dc.subject.keywordAuthor | Debridement | - |
dc.relation.journalResearchArea | Orthopedics | - |
dc.relation.journalWebOfScienceCategory | Orthopedics | - |
dc.description.journalRegisteredClass | scopus | - |
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