Subcentimeter hypervascular nodule with typical imaging findings of hepatocellular carcinoma in patients with history of hepatocellular carcinoma: natural course on serial gadoxetic acid-enhanced MRI and diffusion-weighted imaging
DC Field | Value | Language |
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dc.contributor.author | Song, Kyoung Doo | - |
dc.contributor.author | Kim, Seong Hyun | - |
dc.contributor.author | Lim, Hyo Keun | - |
dc.contributor.author | Jung, Sin-Ho | - |
dc.contributor.author | Sohn, Insuk | - |
dc.contributor.author | Kim, Hyung Sik | - |
dc.date.available | 2020-02-28T08:42:19Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2015-09 | - |
dc.identifier.issn | 0938-7994 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/10182 | - |
dc.description.abstract | Objectives To evaluate the natural course of subcentimeter hypervascular nodules at high risk for developing into hepatocellular carcinomas (SHNHR) using serial magnetic resonance imaging (MRI) in patients with a history of hepatocellular carcinoma (HCC). Methods An SHNHR was defined as a subcentimeter hypervascular nodule having typical imaging findings of HCC on gadoxetic acid-enhanced MRI and diffusion-weighted imaging. We included 39 patients with 46 SHNHRs (mean size +/- standard deviation, 6.1 +/- 1.6 mm; range, 3.2 - 9.0 mm). Overt HCC was defined as pathology proven HCC or a nodule larger than 1 cm with typical imaging findings of HCC. The cumulative rate and the independent predictive factors for progression to overt HCC were evaluated. Results The median follow-up period was 139 days (range, 64 - 392 days). The cumulative progression rate to overt HCC at 3, 6, 9, and 12 months was 13.9 %, 61.7 %, 83.2 %, and 89.9 %. The initial size of SHNHR was a significant predictor of progression to overt HCC, with an optimal cut-off value of 5.5 mm. Conclusion The progression rate of SHNHR to overt HCC within 12 months was high (89.9 %) in patients with history of HCC. The initial size of SHNHR was an important predictor for progression to overt HCC. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER | - |
dc.relation.isPartOf | EUROPEAN RADIOLOGY | - |
dc.subject | GROWTH-RATE | - |
dc.subject | COMPUTED-TOMOGRAPHY | - |
dc.subject | CIRRHOTIC LIVER | - |
dc.subject | TUMOR-GROWTH | - |
dc.subject | DIAGNOSIS | - |
dc.subject | SURVIVAL | - |
dc.subject | SMALLER | - |
dc.subject | LESIONS | - |
dc.subject | TIME | - |
dc.subject | CT | - |
dc.title | Subcentimeter hypervascular nodule with typical imaging findings of hepatocellular carcinoma in patients with history of hepatocellular carcinoma: natural course on serial gadoxetic acid-enhanced MRI and diffusion-weighted imaging | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000359396700033 | - |
dc.identifier.doi | 10.1007/s00330-015-3680-9 | - |
dc.identifier.bibliographicCitation | EUROPEAN RADIOLOGY, v.25, no.9, pp.2789 - 2796 | - |
dc.identifier.scopusid | 2-s2.0-84938970196 | - |
dc.citation.endPage | 2796 | - |
dc.citation.startPage | 2789 | - |
dc.citation.title | EUROPEAN RADIOLOGY | - |
dc.citation.volume | 25 | - |
dc.citation.number | 9 | - |
dc.contributor.affiliatedAuthor | Kim, Hyung Sik | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Subcentimeter | - |
dc.subject.keywordAuthor | Hypervascular nodule | - |
dc.subject.keywordAuthor | Hepatocellular carcinoma | - |
dc.subject.keywordAuthor | Natural course | - |
dc.subject.keywordAuthor | Progression rate | - |
dc.subject.keywordPlus | GROWTH-RATE | - |
dc.subject.keywordPlus | COMPUTED-TOMOGRAPHY | - |
dc.subject.keywordPlus | CIRRHOTIC LIVER | - |
dc.subject.keywordPlus | TUMOR-GROWTH | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | SMALLER | - |
dc.subject.keywordPlus | LESIONS | - |
dc.subject.keywordPlus | TIME | - |
dc.subject.keywordPlus | CT | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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