Overview of CMOS image sensor use in molecular diagnostics
DC Field | Value | Language |
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dc.contributor.author | Devadhasan, Jasmine Pramila | - |
dc.contributor.author | Yoo, In Sang | - |
dc.contributor.author | Kim, Sanghyo | - |
dc.date.available | 2020-02-28T10:41:47Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2015-03 | - |
dc.identifier.issn | 1567-1739 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/10757 | - |
dc.description.abstract | CMOS sensors comprise an important tool in bioscientific applications. This review focuses on CMOS sensor-based molecular diagnostics of DNA, protein, and metabolic molecules. Herein, gene sequencing, DNA-DNA hybridization, single nucleotide polymorphisms (SNP), protein interactions, peptide interactions, antigen-antibody (Ag-Ab) interactions, as well as glucose and cholesterol monitoring using CMOS sensors are discussed along with existing experimental outcomes. CMOS sensor based electrochemical, optical, impedance, dual, continuous, and label-free analysis and their related integration techniques are explained. Moreover, we describe the utilization of a CMOS chip in microarray fabrication, assay platform development, and transducer incorporation for molecular diagnostics. Furthermore, CMOS sensor-based point-of-care (POC) applications, other biological analyses, and the role of nanoparticles in biomolecular sensing are discussed. Future directions include information about the novel integration of CMOS sensor-based molecular diagnostic devices with a central focus towards enhancement of POC approaches. This review is helpful in creating highly sensitive, cheaper, and user-friendly biomedical devices with modern dimensions. (C) 2015 Elsevier B.V. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.relation.isPartOf | CURRENT APPLIED PHYSICS | - |
dc.subject | LABEL-FREE DETECTION | - |
dc.subject | C-REACTIVE PROTEIN | - |
dc.subject | ON-A-CHIP | - |
dc.subject | CELL-PHONE | - |
dc.subject | ELECTROCHEMICAL DETECTION | - |
dc.subject | BIOLOGICAL APPLICATIONS | - |
dc.subject | ELECTRICAL DETECTION | - |
dc.subject | DNA ANALYSIS | - |
dc.subject | SYSTEM | - |
dc.subject | ARRAY | - |
dc.title | Overview of CMOS image sensor use in molecular diagnostics | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000349904900041 | - |
dc.identifier.doi | 10.1016/j.cap.2015.01.009 | - |
dc.identifier.bibliographicCitation | CURRENT APPLIED PHYSICS, v.15, no.3, pp.402 - 411 | - |
dc.identifier.kciid | ART001981020 | - |
dc.identifier.scopusid | 2-s2.0-84921825733 | - |
dc.citation.endPage | 411 | - |
dc.citation.startPage | 402 | - |
dc.citation.title | CURRENT APPLIED PHYSICS | - |
dc.citation.volume | 15 | - |
dc.citation.number | 3 | - |
dc.contributor.affiliatedAuthor | Devadhasan, Jasmine Pramila | - |
dc.contributor.affiliatedAuthor | Yoo, In Sang | - |
dc.contributor.affiliatedAuthor | Kim, Sanghyo | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | CMOS image sensor | - |
dc.subject.keywordAuthor | Molecular diagnostics | - |
dc.subject.keywordAuthor | Point-of-care diagnosis | - |
dc.subject.keywordAuthor | Biochemical detection | - |
dc.subject.keywordAuthor | Biochip | - |
dc.subject.keywordAuthor | Nanoparticles | - |
dc.subject.keywordPlus | LABEL-FREE DETECTION | - |
dc.subject.keywordPlus | C-REACTIVE PROTEIN | - |
dc.subject.keywordPlus | ON-A-CHIP | - |
dc.subject.keywordPlus | CELL-PHONE | - |
dc.subject.keywordPlus | ELECTROCHEMICAL DETECTION | - |
dc.subject.keywordPlus | BIOLOGICAL APPLICATIONS | - |
dc.subject.keywordPlus | ELECTRICAL DETECTION | - |
dc.subject.keywordPlus | DNA ANALYSIS | - |
dc.subject.keywordPlus | SYSTEM | - |
dc.subject.keywordPlus | ARRAY | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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