Abnormal Activation of the Social Brain Network in Children with Autism Spectrum Disorder: An fMRI Study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Sun-Young | - |
dc.contributor.author | Choi, Uk-Su | - |
dc.contributor.author | Park, Sung-Yeon | - |
dc.contributor.author | Oh, Se-Hong | - |
dc.contributor.author | Yoon, Hyo-Woon | - |
dc.contributor.author | Koh, Yun-Joo | - |
dc.contributor.author | Im, Woo-Young | - |
dc.contributor.author | Park, Jee-In | - |
dc.contributor.author | Song, Dong-Ho | - |
dc.contributor.author | Cheon, Keun-Ah | - |
dc.contributor.author | Lee, Chang-Uk | - |
dc.date.available | 2020-02-28T10:44:52Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2015-01 | - |
dc.identifier.issn | 1738-3684 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/10910 | - |
dc.description.abstract | Objective The aim of this study is to investigate abnormal findings of social brain network in Korean children with autism spectrum disorder (ASD) compared with typically developing children (TDC). Methods Functional magnetic resonance imaging (fiVIRI) was performed to examine brain activations during the processing of emotional faces (happy, fearful, and neutral) in 17 children with ASD, 24 TDC. Results When emotional face stimuli were given to children with ASD, various areas of the social brain relevant to social cognition showed reduced activation. Specifically, ASD children exhibited less activation in the right amygdala (AMY), right superior temporal sulcus (STS) and right inferior frontal gyrus (IFG) than TDC group when fearful faces were shown. Activation of left insular cortex and right IFG in response to happy faces was less in the ASD group. Similar findings were also found in left superior insular gyrus and right insula in case of neutral stimulation. Conclusion These findings suggest that children with ASD have different processing of social and emotional experience at the neural level. In other words, the deficit of social cognition in ASD could be explained by the deterioration of the capacity for visual analysis of emotional faces, the subsequent inner imitation through mirror neuron system (MNS), and the ability to transmit it to the limbic system and to process the transmitted emotion. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN NEUROPSYCHIATRIC ASSOC | - |
dc.relation.isPartOf | PSYCHIATRY INVESTIGATION | - |
dc.subject | NEURAL SYSTEMS | - |
dc.subject | INTEROCEPTIVE AWARENESS | - |
dc.subject | DIAGNOSTIC INTERVIEW | - |
dc.subject | ASPERGER-SYNDROME | - |
dc.subject | IMITATION | - |
dc.subject | MECHANISMS | - |
dc.subject | DEFICITS | - |
dc.subject | FACE | - |
dc.subject | METAANALYSIS | - |
dc.subject | ADOLESCENTS | - |
dc.title | Abnormal Activation of the Social Brain Network in Children with Autism Spectrum Disorder: An fMRI Study | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000348258800006 | - |
dc.identifier.doi | 10.4306/pi.2015.12.1.37 | - |
dc.identifier.bibliographicCitation | PSYCHIATRY INVESTIGATION, v.12, no.1, pp.37 - 45 | - |
dc.identifier.kciid | ART002015379 | - |
dc.identifier.scopusid | 2-s2.0-84921950904 | - |
dc.citation.endPage | 45 | - |
dc.citation.startPage | 37 | - |
dc.citation.title | PSYCHIATRY INVESTIGATION | - |
dc.citation.volume | 12 | - |
dc.citation.number | 1 | - |
dc.contributor.affiliatedAuthor | Choi, Uk-Su | - |
dc.contributor.affiliatedAuthor | Park, Sung-Yeon | - |
dc.contributor.affiliatedAuthor | Oh, Se-Hong | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Autism spectrum disorder | - |
dc.subject.keywordAuthor | Social brain network | - |
dc.subject.keywordAuthor | Social cognition | - |
dc.subject.keywordAuthor | fMRI | - |
dc.subject.keywordPlus | NEURAL SYSTEMS | - |
dc.subject.keywordPlus | INTEROCEPTIVE AWARENESS | - |
dc.subject.keywordPlus | DIAGNOSTIC INTERVIEW | - |
dc.subject.keywordPlus | ASPERGER-SYNDROME | - |
dc.subject.keywordPlus | IMITATION | - |
dc.subject.keywordPlus | MECHANISMS | - |
dc.subject.keywordPlus | DEFICITS | - |
dc.subject.keywordPlus | FACE | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | ADOLESCENTS | - |
dc.relation.journalResearchArea | Psychiatry | - |
dc.relation.journalWebOfScienceCategory | Psychiatry | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | ssci | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.