Hepatitis associated with Mycoplasma pneumoniae infection in Korean children: A prospective study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, K.W. | - |
dc.contributor.author | Sung, J.J. | - |
dc.contributor.author | Tchah, H. | - |
dc.contributor.author | Ryoo, E. | - |
dc.contributor.author | Cho, H.K. | - |
dc.contributor.author | Sun, Y.H. | - |
dc.contributor.author | Cho, K.H. | - |
dc.contributor.author | Son, D.W. | - |
dc.contributor.author | Jeon, I.S. | - |
dc.contributor.author | Kim, Y.M. | - |
dc.date.available | 2020-02-28T10:46:20Z | - |
dc.date.created | 2020-02-12 | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 1738-1061 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/11008 | - |
dc.description.abstract | Purpose: Mycoplasma pneumoniae (MP) infection is a major cause of respiratory infection in school-aged children. Extrapulmonary manifestations of MP infection are common, but liver involvement has been rarely reported. The aim of this study was to determine the clinical characteristics of MP-associated hepatitis. Methods: This prospective study included 1,044 pediatric patients with MP infection diagnosed serologically with IgM at one medical center from January 2006 to December 2012. Eighty of these patients had elevated levels of serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT), each greater than 50 IU/L, without any other specific liver disorder and were compared with the 964 children without liver disorders. Results: In total, 7.7% of patients with MP infection had a diagnosis of hepatitis, especially in fall and winter. The ratio of male to female patients was 1.7:1, and the mean age of the patients was 5 years and 5 months. The most common symptoms were cough, fever, and sputum. Anorexia was the most common gastrointestinal symptom, followed by nausea/vomiting, diarrhea, and abdominal pain. Mean levels of AST and ALT were 100.65 IU/L and 118.73 IU/L, respectively. Serum AST/ALT level was normalized within 7.5 days on average without complications. The mean duration of hospitalization (11.3 days) was longer for children with hepatitis than for those without hepatitis (P =0.034). Conclusion: MP-associated hepatitis is not uncommon and has a relatively good prognosis. Therefore, clinicians should be concerned about liver involvement in MP infection but avoid further unnecessary evaluation of hepatitis associated with MP. © 2015 by The Korean Pediatric Society. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Korean Pediatric Society | - |
dc.relation.isPartOf | Korean Journal of Pediatrics | - |
dc.subject | C reactive protein | - |
dc.subject | roxithromycin | - |
dc.subject | abdominal pain | - |
dc.subject | adolescent | - |
dc.subject | alanine aminotransferase blood level | - |
dc.subject | anorexia | - |
dc.subject | Article | - |
dc.subject | aspartate aminotransferase blood level | - |
dc.subject | child | - |
dc.subject | controlled study | - |
dc.subject | coughing | - |
dc.subject | diarrhea | - |
dc.subject | disease association | - |
dc.subject | enzyme immunoassay | - |
dc.subject | erythrocyte sedimentation rate | - |
dc.subject | female | - |
dc.subject | fever | - |
dc.subject | hepatitis | - |
dc.subject | human | - |
dc.subject | infant | - |
dc.subject | Korean (people) | - |
dc.subject | lung infiltrate | - |
dc.subject | major clinical study | - |
dc.subject | male | - |
dc.subject | Mycoplasma pneumonia | - |
dc.subject | nausea and vomiting | - |
dc.subject | prospective study | - |
dc.subject | respiratory distress | - |
dc.subject | sputum | - |
dc.subject | treatment outcome | - |
dc.title | Hepatitis associated with Mycoplasma pneumoniae infection in Korean children: A prospective study | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.doi | 10.3345/kjp.2015.58.6.211 | - |
dc.identifier.bibliographicCitation | Korean Journal of Pediatrics, v.58, no.6, pp.211 - 217 | - |
dc.identifier.kciid | ART001998493 | - |
dc.identifier.scopusid | 2-s2.0-84931426336 | - |
dc.citation.endPage | 217 | - |
dc.citation.startPage | 211 | - |
dc.citation.title | Korean Journal of Pediatrics | - |
dc.citation.volume | 58 | - |
dc.citation.number | 6 | - |
dc.contributor.affiliatedAuthor | Kim, K.W. | - |
dc.contributor.affiliatedAuthor | Sung, J.J. | - |
dc.contributor.affiliatedAuthor | Tchah, H. | - |
dc.contributor.affiliatedAuthor | Ryoo, E. | - |
dc.contributor.affiliatedAuthor | Cho, H.K. | - |
dc.contributor.affiliatedAuthor | Sun, Y.H. | - |
dc.contributor.affiliatedAuthor | Cho, K.H. | - |
dc.contributor.affiliatedAuthor | Son, D.W. | - |
dc.contributor.affiliatedAuthor | Jeon, I.S. | - |
dc.contributor.affiliatedAuthor | Kim, Y.M. | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Hepatitis | - |
dc.subject.keywordAuthor | Macrolides | - |
dc.subject.keywordAuthor | Mycoplasma pneumoniae | - |
dc.subject.keywordPlus | C reactive protein | - |
dc.subject.keywordPlus | roxithromycin | - |
dc.subject.keywordPlus | abdominal pain | - |
dc.subject.keywordPlus | adolescent | - |
dc.subject.keywordPlus | alanine aminotransferase blood level | - |
dc.subject.keywordPlus | anorexia | - |
dc.subject.keywordPlus | Article | - |
dc.subject.keywordPlus | aspartate aminotransferase blood level | - |
dc.subject.keywordPlus | child | - |
dc.subject.keywordPlus | controlled study | - |
dc.subject.keywordPlus | coughing | - |
dc.subject.keywordPlus | diarrhea | - |
dc.subject.keywordPlus | disease association | - |
dc.subject.keywordPlus | enzyme immunoassay | - |
dc.subject.keywordPlus | erythrocyte sedimentation rate | - |
dc.subject.keywordPlus | female | - |
dc.subject.keywordPlus | fever | - |
dc.subject.keywordPlus | hepatitis | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | infant | - |
dc.subject.keywordPlus | Korean (people) | - |
dc.subject.keywordPlus | lung infiltrate | - |
dc.subject.keywordPlus | major clinical study | - |
dc.subject.keywordPlus | male | - |
dc.subject.keywordPlus | Mycoplasma pneumonia | - |
dc.subject.keywordPlus | nausea and vomiting | - |
dc.subject.keywordPlus | prospective study | - |
dc.subject.keywordPlus | respiratory distress | - |
dc.subject.keywordPlus | sputum | - |
dc.subject.keywordPlus | treatment outcome | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.