Smart point-of-care systems for molecular diagnostics based on nanotechnology: Whole blood glucose analysis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Devadhasan, J.P. | - |
dc.contributor.author | Kim, S. | - |
dc.date.available | 2020-02-28T10:46:33Z | - |
dc.date.created | 2020-02-12 | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 1605-7422 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/11016 | - |
dc.description.abstract | Complementary metal oxide semiconductor (CMOS) image sensors are received great attention for their high efficiency in biological applications. The present work describes a CMOS image sensor-based whole blood glucose monitoring system through a point-of-care (POC) approach. A simple poly-ethylene terephthalate (PET) film chip was developed to carry out the enzyme kinetic reaction at various concentrations of blood glucose. In this technique, assay reagent was adsorbed onto amine functionalized silica (AFSiO2) nanoparticles in order to achieve glucose oxidation on the PET film chip. The AFSiO2 nanoparticles can immobilize the assay reagent with an electrostatic attraction and eased to develop the opaque platform which was technically suitable chip to analyze by the camera module. The oxidized glucose then produces a green color according to the glucose concentration and is analyzed by the camera module as a photon detection technique. The photon number decreases with increasing glucose concentration. The simple sensing approach, utilizing enzyme immobilized AFSiO2 nanoparticle chip and assay detection method was developed for quantitative glucose measurement. © 2015 SPIE. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | SPIE | - |
dc.relation.isPartOf | Progress in Biomedical Optics and Imaging - Proceedings of SPIE | - |
dc.subject | Blood | - |
dc.subject | Cameras | - |
dc.subject | CMOS integrated circuits | - |
dc.subject | Digital cameras | - |
dc.subject | Enzymes | - |
dc.subject | Ethylene | - |
dc.subject | Image sensors | - |
dc.subject | Metals | - |
dc.subject | MOS devices | - |
dc.subject | Nanoparticles | - |
dc.subject | Nanosensors | - |
dc.subject | Photodetectors | - |
dc.subject | Photons | - |
dc.subject | Blood glucose sensing | - |
dc.subject | CMOS image sensor | - |
dc.subject | Kinetic reactions | - |
dc.subject | PET films | - |
dc.subject | Photon detection | - |
dc.subject | Glucose | - |
dc.title | Smart point-of-care systems for molecular diagnostics based on nanotechnology: Whole blood glucose analysis | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000359600900001 | - |
dc.identifier.doi | 10.1117/12.2189576 | - |
dc.identifier.bibliographicCitation | Progress in Biomedical Optics and Imaging - Proceedings of SPIE, v.9523 | - |
dc.identifier.scopusid | 2-s2.0-84938702046 | - |
dc.citation.title | Progress in Biomedical Optics and Imaging - Proceedings of SPIE | - |
dc.citation.volume | 9523 | - |
dc.contributor.affiliatedAuthor | Devadhasan, J.P. | - |
dc.contributor.affiliatedAuthor | Kim, S. | - |
dc.type.docType | Proceedings Paper | - |
dc.subject.keywordAuthor | AFSiO2 nanoparticles | - |
dc.subject.keywordAuthor | Blood glucose sensing | - |
dc.subject.keywordAuthor | CMOS image sensor | - |
dc.subject.keywordAuthor | Enzyme kinetic reaction | - |
dc.subject.keywordAuthor | PET film chip | - |
dc.subject.keywordAuthor | Photon detection. | - |
dc.subject.keywordPlus | Blood | - |
dc.subject.keywordPlus | Cameras | - |
dc.subject.keywordPlus | CMOS integrated circuits | - |
dc.subject.keywordPlus | Digital cameras | - |
dc.subject.keywordPlus | Enzymes | - |
dc.subject.keywordPlus | Ethylene | - |
dc.subject.keywordPlus | Image sensors | - |
dc.subject.keywordPlus | Metals | - |
dc.subject.keywordPlus | MOS devices | - |
dc.subject.keywordPlus | Nanoparticles | - |
dc.subject.keywordPlus | Nanosensors | - |
dc.subject.keywordPlus | Photodetectors | - |
dc.subject.keywordPlus | Photons | - |
dc.subject.keywordPlus | Blood glucose sensing | - |
dc.subject.keywordPlus | CMOS image sensor | - |
dc.subject.keywordPlus | Kinetic reactions | - |
dc.subject.keywordPlus | PET films | - |
dc.subject.keywordPlus | Photon detection | - |
dc.subject.keywordPlus | Glucose | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Optics | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalResearchArea | Spectroscopy | - |
dc.relation.journalWebOfScienceCategory | Engineering, Biomedical | - |
dc.relation.journalWebOfScienceCategory | Optics | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Spectroscopy | - |
dc.description.journalRegisteredClass | scopus | - |
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