Active Molecular Chitosan (AMC-S1): Preparation and Characterization of Antibacterial Activity
DC Field | Value | Language |
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dc.contributor.author | 김주원 | - |
dc.contributor.author | 이춘근 | - |
dc.contributor.author | 황유진 | - |
dc.contributor.author | 박제권 | - |
dc.date.available | 2020-02-28T11:43:46Z | - |
dc.date.created | 2020-02-12 | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 1229-4160 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/11242 | - |
dc.description.abstract | The aim of the present study is to prepare the chitosan hydrolysates and characterize their potential antibacterial activity. High molecular weight chitosan (CTSN-H) and medium molecular weight chitosan (MMWC, 2~10-kDa) were further degraded efficiently by using chitosanase from Bacillus subtilis JH-1122. Molecular weight (MW) of the final product was determined by MALDI-TOF MS, showed several peaks ranging from 0.8 to 2.5-kDa. Based on antibacterial activity of the hydrolysates, final products were named as active molecular chitosan (AMC-S1). AMC-S1 was evaluated as IC50 to 12.5 μg/mL of the concentration toward Candida albicans. Our present study demonstrates that AMC-S1 derived from the digestion of CTSN-H and MMWC can be selected as a potent factor affecting on antimicrobial activity against C. albicans for the industry and pharmaceutical applications. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | 한국키틴키토산학회 | - |
dc.relation.isPartOf | Journal of Chitin and Chitosan | - |
dc.title | Active Molecular Chitosan (AMC-S1): Preparation and Characterization of Antibacterial Activity | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 2 | - |
dc.identifier.doi | 10.17642/jcc.20.4.9 | - |
dc.identifier.bibliographicCitation | Journal of Chitin and Chitosan, v.20, no.4, pp.280 - 286 | - |
dc.identifier.kciid | ART002063183 | - |
dc.citation.endPage | 286 | - |
dc.citation.startPage | 280 | - |
dc.citation.title | Journal of Chitin and Chitosan | - |
dc.citation.volume | 20 | - |
dc.citation.number | 4 | - |
dc.contributor.affiliatedAuthor | 김주원 | - |
dc.contributor.affiliatedAuthor | 이춘근 | - |
dc.contributor.affiliatedAuthor | 황유진 | - |
dc.contributor.affiliatedAuthor | 박제권 | - |
dc.subject.keywordAuthor | Active molecular chitosan (AMC-S1) | - |
dc.subject.keywordAuthor | Chitosanase | - |
dc.subject.keywordAuthor | MALDI-TOF MS | - |
dc.subject.keywordAuthor | Candida albicans | - |
dc.subject.keywordAuthor | antibacterial activity | - |
dc.description.journalRegisteredClass | kci | - |
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