2000년 이후 갑상선 기능저하증에 대한 국내 한의학 실험연구 체계적 고찰

Abstract

Objectives: The purpose of this study was to investigate the experimental studies which was performed by single or complex herbal medicines on hypothyroidism. Methods: I searched the domestic experimental studies about single or complex herbal medicines' effects on hypothyroidism that published since 2000 on 4 Korean databases by keywords, ‘thyroid gland', ‘hypofunction', ‘hypothyroidism'. Results: 11 single herbal medicines and 9 complex herbal medicines in 20 experimental studies have reported their effectiveness and safetiness in PTU-induced hypothyroidism rats by evaluating the changes of several biochemical and hematological indexes. Conclusions: In order to make new and more effective medicines on hypothyroidism, there should be further studies by using combinations of herbal medicines and the differences of their mechanisms.