Plant-Derived Compounds Targeting Pancreatic Beta Cells for the Treatment of Diabetes
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Oh, Yoon Sin | - |
dc.date.available | 2020-02-28T15:41:48Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 1741-427X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/11960 | - |
dc.description.abstract | Diabetes is a global health problem and a national economic burden. Although several antidiabetic drugs are available, the need for novel therapeutic agents with improved efficacy and few side effects remains. Drugs derived from natural compounds are more attractive than synthetic drugs because of their diversity and minimal side effects. This review summarizes the most relevant effects of various plant-derived natural compounds on the functionality of pancreatic beta cells. Published data suggest that natural compounds directly enhance insulin secretion, prevent pancreatic beta cell apoptosis, and modulate pancreatic beta cell differentiation and proliferation. It is essential to continuously investigate natural compounds as sources of novel pharmaceuticals. Therefore, more studies into these compounds' mechanisms of action are warranted for their development as potential anti-diabetics. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | HINDAWI LTD | - |
dc.relation.isPartOf | EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | - |
dc.subject | STIMULATES INSULIN-SECRETION | - |
dc.subject | MOMORDICA-CHARANTIA | - |
dc.subject | GYMNEMA-SYLVESTRE | - |
dc.subject | GREEN TEA | - |
dc.subject | HYPOGLYCEMIC ACTIVITY | - |
dc.subject | IMPROVES GLUCOSE | - |
dc.subject | DOUBLE-BLIND | - |
dc.subject | ANTIHYPERGLYCEMIC ACTIVITY | - |
dc.subject | EPIGALLOCATECHIN GALLATE | - |
dc.subject | OXIDATIVE STRESS | - |
dc.title | Plant-Derived Compounds Targeting Pancreatic Beta Cells for the Treatment of Diabetes | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000364711500001 | - |
dc.identifier.doi | 10.1155/2015/629863 | - |
dc.identifier.bibliographicCitation | EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | - |
dc.identifier.scopusid | 2-s2.0-84947461134 | - |
dc.citation.title | EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | - |
dc.contributor.affiliatedAuthor | Oh, Yoon Sin | - |
dc.type.docType | Review | - |
dc.subject.keywordPlus | STIMULATES INSULIN-SECRETION | - |
dc.subject.keywordPlus | MOMORDICA-CHARANTIA | - |
dc.subject.keywordPlus | GYMNEMA-SYLVESTRE | - |
dc.subject.keywordPlus | GREEN TEA | - |
dc.subject.keywordPlus | HYPOGLYCEMIC ACTIVITY | - |
dc.subject.keywordPlus | IMPROVES GLUCOSE | - |
dc.subject.keywordPlus | DOUBLE-BLIND | - |
dc.subject.keywordPlus | ANTIHYPERGLYCEMIC ACTIVITY | - |
dc.subject.keywordPlus | EPIGALLOCATECHIN GALLATE | - |
dc.subject.keywordPlus | OXIDATIVE STRESS | - |
dc.relation.journalResearchArea | Integrative & Complementary Medicine | - |
dc.relation.journalWebOfScienceCategory | Integrative & Complementary Medicine | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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