Dopamine-functionalized InP/ZnS quantum dots as fluorescence probes for the detection of adenosine in microfluidic chip
DC Field | Value | Language |
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dc.contributor.author | Ankireddy, Seshadri Reddy | - |
dc.contributor.author | Kim, Jongsung | - |
dc.date.available | 2020-02-28T15:42:06Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2015-08 | - |
dc.identifier.issn | 1178-2013 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/11975 | - |
dc.description.abstract | Microbeads are frequently used as solid supports for biomolecules such as proteins and nucleic acids in heterogeneous microfluidic assays. Chip-based, quantum dot (QD)-bead-biomolecule probes have been used for the detection of various types of DNA. In this study, we developed dopamine (DA)-functionalized InP/ZnS QDs (QDs-DA) as fluorescence probes for the detection of adenosine in microfluidic chips. The photoluminescence (PL) intensity of the QDs-DA is quenched by Zn2+ because of the strong coordination interactions. In the presence of adenosine, Zn2+ cations preferentially bind to adenosine, and the PL intensity of the QDs-DA is recovered. A polydimethylsiloxane-based microfluidic chip was fabricated, and adenosine detection was confirmed using QDs-DA probes. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | DOVE MEDICAL PRESS LTD | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF NANOMEDICINE | - |
dc.title | Dopamine-functionalized InP/ZnS quantum dots as fluorescence probes for the detection of adenosine in microfluidic chip | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000365122300013 | - |
dc.identifier.doi | 10.2147/IJN.S88465 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF NANOMEDICINE, v.10, pp.121 - 128 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-84947421177 | - |
dc.citation.endPage | 128 | - |
dc.citation.startPage | 121 | - |
dc.citation.title | INTERNATIONAL JOURNAL OF NANOMEDICINE | - |
dc.citation.volume | 10 | - |
dc.contributor.affiliatedAuthor | Ankireddy, Seshadri Reddy | - |
dc.contributor.affiliatedAuthor | Kim, Jongsung | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | quantum dots | - |
dc.subject.keywordAuthor | photoluminescence | - |
dc.subject.keywordAuthor | microfluidic chip | - |
dc.subject.keywordAuthor | adenosine | - |
dc.subject.keywordAuthor | mercaptopropionic acid | - |
dc.subject.keywordAuthor | mercaptoundecanoic acid | - |
dc.subject.keywordAuthor | PDMS | - |
dc.subject.keywordPlus | OPTICAL-PROPERTIES | - |
dc.subject.keywordPlus | P53 GENE | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | PHENYLALANINE | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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