Synthesis and anti-bacterial activity of AuNRs-PS-MNPs

Abstract

Novel, recyclable anti-bacterial Janus particles (AuNRs-PS-MNPs) were produced successfully by combination of a confined convective assembly method and modified layer-by-layer technology. The Janus particles, one hemisphere of polystyrene coated by gold nanorods (AuNRs) and the other was coated by magnetic nanoparticles (MNPs), have both the properties of AuNRs and MNPs, therefore AuNRs-PS-MNPs could be collected by a magnet and produce heat under NIR irradiation. The survival rate of Escherichia coli (E. coli) and Staphylococcus epidermidis (S. epidermidis) treated with AuNRs-PS-MNPs and NIR were investigated using live/dead staining techniques, which confirmed the novel Janus particles worked as an efficient antibacterial agent. (C) 2014 Elsevier B.V. All rights reserved.