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The first synthesis of the antiangiogenic homoisoflavanone, cremastranone
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Lee, Bit | - |
| dc.contributor.author | Basavarajappa, Halesha D. | - |
| dc.contributor.author | Sulaiman, Rania S. | - |
| dc.contributor.author | Fei, Xiang | - |
| dc.contributor.author | Seo, Seung-Yong | - |
| dc.contributor.author | Corson, Timothy W. | - |
| dc.date.available | 2020-02-28T15:46:00Z | - |
| dc.date.created | 2020-02-06 | - |
| dc.date.issued | 2014-10-21 | - |
| dc.identifier.issn | 1477-0520 | - |
| dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/12192 | - |
| dc.description.abstract | An antiangiogenic homoisoflavanone, cremastranone, was synthesized for the first time. This scalable synthesis, which includes selective demethylation, could be used to develop lead molecules to treat angiogenesis-induced eye diseases. Synthetic cremastranone inhibited the proliferation, migration and tube formation ability of human retinal microvascular endothelial cells, important steps in pathological angiogenesis. | - |
| dc.language | 영어 | - |
| dc.language.iso | en | - |
| dc.publisher | ROYAL SOC CHEMISTRY | - |
| dc.relation.isPartOf | ORGANIC & BIOMOLECULAR CHEMISTRY | - |
| dc.subject | NEOVASCULARIZATION | - |
| dc.subject | INHIBITION | - |
| dc.subject | THERAPY | - |
| dc.title | The first synthesis of the antiangiogenic homoisoflavanone, cremastranone | - |
| dc.type | Article | - |
| dc.type.rims | ART | - |
| dc.description.journalClass | 1 | - |
| dc.identifier.wosid | 000342886000003 | - |
| dc.identifier.doi | 10.1039/c4ob01604a | - |
| dc.identifier.bibliographicCitation | ORGANIC & BIOMOLECULAR CHEMISTRY, v.12, no.39, pp.7673 - 7677 | - |
| dc.identifier.scopusid | 2-s2.0-84907882647 | - |
| dc.citation.endPage | 7677 | - |
| dc.citation.startPage | 7673 | - |
| dc.citation.title | ORGANIC & BIOMOLECULAR CHEMISTRY | - |
| dc.citation.volume | 12 | - |
| dc.citation.number | 39 | - |
| dc.contributor.affiliatedAuthor | Lee, Bit | - |
| dc.contributor.affiliatedAuthor | Fei, Xiang | - |
| dc.contributor.affiliatedAuthor | Seo, Seung-Yong | - |
| dc.type.docType | Article | - |
| dc.subject.keywordPlus | NEOVASCULARIZATION | - |
| dc.subject.keywordPlus | INHIBITION | - |
| dc.subject.keywordPlus | THERAPY | - |
| dc.relation.journalResearchArea | Chemistry | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
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Related Researcher
- Seo, Seung Yong
- Pharmacy (Dept.of Pharmacy)