In-depth metabolic phenotyping of genetically engineered mouse models in obesity and diabetes
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Hui-Young | - |
dc.contributor.author | Jeong, Kyeong-Hoon | - |
dc.contributor.author | Choi, Cheol Soo | - |
dc.date.available | 2020-02-28T16:41:55Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2014-10 | - |
dc.identifier.issn | 0938-8990 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/12247 | - |
dc.description.abstract | The world-wide prevalence of obesity and diabetes has increased sharply during the last two decades. Accordingly, the metabolic phenotyping of genetically engineered mouse models is critical for evaluating the functional roles of target genes in obesity and diabetes, and for developing new therapeutic targets. In this review, we discuss the practical meaning of metabolic phenotyping, the strategy of choosing appropriate tests, and considerations when designing and performing metabolic phenotyping in mice. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER | - |
dc.relation.isPartOf | MAMMALIAN GENOME | - |
dc.subject | NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENASE | - |
dc.subject | INDUCED HEPATIC STEATOSIS | - |
dc.subject | BODY-COMPOSITION ANALYSIS | - |
dc.subject | X-RAY ABSORPTIOMETRY | - |
dc.subject | DIET-INDUCED OBESITY | - |
dc.subject | INSULIN-RESISTANCE | - |
dc.subject | GLUCOSE-METABOLISM | - |
dc.subject | KNOCKOUT MICE | - |
dc.subject | C57BL/6 SUBSTRAINS | - |
dc.subject | CARDIOVASCULAR-DISEASE | - |
dc.title | In-depth metabolic phenotyping of genetically engineered mouse models in obesity and diabetes | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000342173700014 | - |
dc.identifier.doi | 10.1007/s00335-014-9520-4 | - |
dc.identifier.bibliographicCitation | MAMMALIAN GENOME, v.25, no.9-10, pp.508 - 521 | - |
dc.identifier.scopusid | 2-s2.0-84929506896 | - |
dc.citation.endPage | 521 | - |
dc.citation.startPage | 508 | - |
dc.citation.title | MAMMALIAN GENOME | - |
dc.citation.volume | 25 | - |
dc.citation.number | 9-10 | - |
dc.contributor.affiliatedAuthor | Lee, Hui-Young | - |
dc.contributor.affiliatedAuthor | Jeong, Kyeong-Hoon | - |
dc.contributor.affiliatedAuthor | Choi, Cheol Soo | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENASE | - |
dc.subject.keywordPlus | INDUCED HEPATIC STEATOSIS | - |
dc.subject.keywordPlus | BODY-COMPOSITION ANALYSIS | - |
dc.subject.keywordPlus | X-RAY ABSORPTIOMETRY | - |
dc.subject.keywordPlus | DIET-INDUCED OBESITY | - |
dc.subject.keywordPlus | INSULIN-RESISTANCE | - |
dc.subject.keywordPlus | GLUCOSE-METABOLISM | - |
dc.subject.keywordPlus | KNOCKOUT MICE | - |
dc.subject.keywordPlus | C57BL/6 SUBSTRAINS | - |
dc.subject.keywordPlus | CARDIOVASCULAR-DISEASE | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Genetics & Heredity | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Genetics & Heredity | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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