Nocatriones A and B, Photoprotective Tetracenediones from a Marine-Derived Nocardiopsis sp.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Min Cheol | - |
dc.contributor.author | Hwang, Eunson | - |
dc.contributor.author | Kim, Taejung | - |
dc.contributor.author | Ham, Jungyeob | - |
dc.contributor.author | Kim, Sun Yeou | - |
dc.contributor.author | Kwon, Hak Cheol | - |
dc.date.available | 2020-02-28T16:42:08Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2014-10 | - |
dc.identifier.issn | 0163-3864 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/12258 | - |
dc.description.abstract | Two new tetracenedione derivatives, nocatriones A (1) and B (2), were discovered from the culture broth of a marine actinomycete, Nocardiopsis sp. KMF-002, which was isolated from the tissue of an unidentified dark purple marine sponge. The structures of 1 and 2, which are tetracenediones containing a-pyrone substituents, were determined to be 3,8,10,11-tetrahydroxy-2-(4-hydroxy-2-oxo-2H-pyran-6-yl)-1-methyltetracene-5,12-dione (1) and 3,8,10,12-tetrahydroxy-2-(4-hydroxy-2-oxo-2H-pyran-6-yl)-1-methyltetracene-6,11-dione (2). Ultraviolet B (UVB)-irradiated cells treated with 10 mu M nocatrione A (1) significantly decreased the level of MMP-1, a protein that degrades collagen and other extracelluar matrix components that comprise dermal tissue, when compared to untreated cells. These results support that nocatriones A (1) and B (2) may show antiphotoaging activity in UVB-irradiated models. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.relation.isPartOf | JOURNAL OF NATURAL PRODUCTS | - |
dc.subject | SKIN | - |
dc.subject | IRRADIATION | - |
dc.subject | MECHANISMS | - |
dc.title | Nocatriones A and B, Photoprotective Tetracenediones from a Marine-Derived Nocardiopsis sp. | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000343786100023 | - |
dc.identifier.doi | 10.1021/np5006086 | - |
dc.identifier.bibliographicCitation | JOURNAL OF NATURAL PRODUCTS, v.77, no.10, pp.2326 - 2330 | - |
dc.identifier.scopusid | 2-s2.0-84908655218 | - |
dc.citation.endPage | 2330 | - |
dc.citation.startPage | 2326 | - |
dc.citation.title | JOURNAL OF NATURAL PRODUCTS | - |
dc.citation.volume | 77 | - |
dc.citation.number | 10 | - |
dc.contributor.affiliatedAuthor | Kim, Sun Yeou | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | SKIN | - |
dc.subject.keywordPlus | IRRADIATION | - |
dc.subject.keywordPlus | MECHANISMS | - |
dc.relation.journalResearchArea | Plant Sciences | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Plant Sciences | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.