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Ultrafast colorimetric detection of nucleic acids based on the inhibition of the oxidase activity of cerium oxide nanoparticles

Authors
Kim, Moon IlPark, Ki SooPark, Hyun Gyu
Issue Date
28-Aug-2014
Publisher
ROYAL SOC CHEMISTRY
Citation
CHEMICAL COMMUNICATIONS, v.50, no.67, pp.9577 - 9580
Journal Title
CHEMICAL COMMUNICATIONS
Volume
50
Number
67
Start Page
9577
End Page
9580
URI
https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/12373
DOI
10.1039/c4cc03841j
ISSN
1359-7345
Abstract
A label-free colorimetric method to detect nucleic acids, which relies on target DNA induced shielding of the oxidase activity of CeO2 NPs, is developed. With this novel strategy, target nucleic acids can be identified within a few minutes and without the need for post-purification of PCR products.
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BioNano Technology (Department of BioNano Technology)
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