beta-Catenin Activated Hepatocellular Adenoma: A Report of Three Cases in Korea
DC Field | Value | Language |
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dc.contributor.author | Kim, Gi Jeong | - |
dc.contributor.author | Seok, Jae Yeon | - |
dc.contributor.author | Rhee, Hyungjin | - |
dc.contributor.author | Choi, Jin-Young | - |
dc.contributor.author | Choi, Jin-Sub | - |
dc.contributor.author | Kim, Kyung Sik | - |
dc.contributor.author | Thung, Swan | - |
dc.contributor.author | Park, Young Nyun | - |
dc.date.available | 2020-02-28T16:47:35Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2014-07 | - |
dc.identifier.issn | 1976-2283 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/12521 | - |
dc.description.abstract | Hepatocellular adenoma (HCA) is an uncommon benign hepatic tumor, and the use of oral contraceptives is known to contribute to the development of HCA. Recently, a genotype and phenotype classification system for HCA was suggested, and Malignant transformation to hepatocellular carcinoma (HCC) was shown to be strongly associated with activating mutations in beta-catenin. Here, we report three cases of HCA in Korean patients: 7-cm, inflammatory and beta-catenin-activated HCA with HCC transformation in a 46-year-old man; 13-cm, beta-catenin-activated HCA with cytological atypia in a 23-year-old woman; and 10-cm, pigmented, inflammatory and p-catenin-activated HCA in a 36-year-old man. All cases exhibited the nuclear expression of beta-catenin and diffuse cytoplasmic expression of glutamine synthetase upon immunohistochemical staining. All tumors were completely resected, and the patients were followed for 3 to 6 years with no evidence of local recurrence or metastasis. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | EDITORIAL OFFICE GUT & LIVER | - |
dc.relation.isPartOf | GUT AND LIVER | - |
dc.subject | CLASSIFICATION | - |
dc.subject | GLYPICAN-3 | - |
dc.subject | EXPRESSION | - |
dc.subject | NODULES | - |
dc.subject | LIVER | - |
dc.title | beta-Catenin Activated Hepatocellular Adenoma: A Report of Three Cases in Korea | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000338396600019 | - |
dc.identifier.doi | 10.5009/gnl.2014.8.4.452 | - |
dc.identifier.bibliographicCitation | GUT AND LIVER, v.8, no.4, pp.452 - 458 | - |
dc.identifier.kciid | ART001896129 | - |
dc.identifier.scopusid | 2-s2.0-84903703569 | - |
dc.citation.endPage | 458 | - |
dc.citation.startPage | 452 | - |
dc.citation.title | GUT AND LIVER | - |
dc.citation.volume | 8 | - |
dc.citation.number | 4 | - |
dc.contributor.affiliatedAuthor | Seok, Jae Yeon | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Adenoma | - |
dc.subject.keywordAuthor | liver cell | - |
dc.subject.keywordAuthor | Beta catenin | - |
dc.subject.keywordAuthor | Carcinoma | - |
dc.subject.keywordAuthor | hepatocellular | - |
dc.subject.keywordAuthor | Glutamine synthetase | - |
dc.subject.keywordPlus | CLASSIFICATION | - |
dc.subject.keywordPlus | GLYPICAN-3 | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | NODULES | - |
dc.subject.keywordPlus | LIVER | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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