The Effect of Body Mass Index on Survival in Advanced Epithelial Ovarian Cancer
- Authors
- Bae, Hyo Sook; Hong, Jin Hwa; Ki, Kyoung-Do; Song, Jae Yun; Shin, Jin Woo; Lee, Jong Min; Lee, Jae Kwan; Lee, Nak Woo; Lee, Chan; Lee, Kyu Wan; Kim, Yong Min
- Issue Date
- Jun-2014
- Publisher
- KOREAN ACAD MEDICAL SCIENCES
- Keywords
- Ovarian Neoplasms; Survival; Body Mass Index; Obesity
- Citation
- JOURNAL OF KOREAN MEDICAL SCIENCE, v.29, no.6, pp.793 - 797
- Journal Title
- JOURNAL OF KOREAN MEDICAL SCIENCE
- Volume
- 29
- Number
- 6
- Start Page
- 793
- End Page
- 797
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/12557
- DOI
- 10.3346/jkms.2014.29.6.793
- ISSN
- 1011-8934
- Abstract
- Controversy remains regarding the effect of obesity on the survival of patients with ovarian cancer in Asia. This study examined the impact of obesity on the survival outcomes in advanced epithelial ovarian cancer (EOC) using Asian body mass index (BMI) criteria. The medical records of patients undergoing surgery for advanced (stage III and IV) EOC were reviewed. Statistical analyses included ANOVA, chi-square test, Kaplan-Meier survival and Cox regression analysis. Among all 236 patients, there were no differences in overall survival according to BMI except in underweight patients. In a multivariate Cox analysis, surgical optimality and underweight status were independent and significant prognostic factors for survival (HR, 2.302; 95% CI, 1.326-3.995; P = 0.003 and HR, 8.622; 95% CI, 1.871-39.737; P = 0.006, respectively). In the subgroup of serous histology and optimal surgery, overweight and obese I patients showed better survival than normal weight patients (P = 0.012). We found that underweight BMI and surgical optimality are independent risk factors for the survival of patients with advanced ovarian cancer. High BMI groups (overweight, obese I and II) are not associated with the survival of advanced EOC patient. However, in the subgroup of EOC patients with serous histology and after optimal operation, overweight and obese I group patients show better survival than the normal weight group patients.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 의과대학 > 의학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/12557)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.