Antiviral Effect of Flavonol Glycosides Isolated from the Leaf of Zanthoxylum piperitum on Influenza Virus
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ha, Song-Yi | - |
dc.contributor.author | Youn, Hana | - |
dc.contributor.author | Song, Chang-Seon | - |
dc.contributor.author | Kang, Se Chan | - |
dc.contributor.author | Bae, Jong Jin | - |
dc.contributor.author | Kim, Hee Tae | - |
dc.contributor.author | Lee, Kwang Min | - |
dc.contributor.author | Eom, Tae Loon | - |
dc.contributor.author | Kim, In Su | - |
dc.contributor.author | Kwak, Jong Hwan | - |
dc.date.available | 2020-02-28T17:45:41Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2014-04 | - |
dc.identifier.issn | 1225-8873 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/12738 | - |
dc.description.abstract | The ethanol extract of Zanthoxylum piperitum (L.) DC. showed in vitro antiviral activity against influenza A virus. Three flavonol glycosides were isolated from the EtOAc fraction of Z. piperitum leaf by means of activity-guided chromatographic separation. Structures of isolated compounds were identified as quercetin 3-O-beta-D-galactopyranoside (1), quercetin 3-O-alpha-L-rhamnopyranoside (2), kaempferol 3-O-alpha-L-rhamnopyranoside (3) by comparing their spectral data with literature values. The anti-influenza viral activity of isolates was evaluated using a plaque reduction assay against influenza A/NWS/33 (H1N1) virus. The compounds also were subjected to neuraminidase inhibition assay in influenza A/NWS/33 virus. Compounds 1-3 exhibited antiviral activity against an influenza A virus in vitro, and inhibited the neuraminidase activity at relatively high concentrations. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MICROBIOLOGICAL SOCIETY KOREA | - |
dc.relation.isPartOf | JOURNAL OF MICROBIOLOGY | - |
dc.subject | ALIPHATIC ACID-AMIDES | - |
dc.subject | RESISTANT STAPHYLOCOCCUS-AUREUS | - |
dc.subject | RAW 264.7 CELLS | - |
dc.subject | INHIBITORY-ACTIVITIES | - |
dc.subject | IN-VITRO | - |
dc.subject | YOUNG LEAVES | - |
dc.subject | MAP KINASE | - |
dc.subject | A VIRUS | - |
dc.subject | DC. | - |
dc.subject | PLANTS | - |
dc.title | Antiviral Effect of Flavonol Glycosides Isolated from the Leaf of Zanthoxylum piperitum on Influenza Virus | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000333574600011 | - |
dc.identifier.doi | 10.1007/s12275-014-4073-5 | - |
dc.identifier.bibliographicCitation | JOURNAL OF MICROBIOLOGY, v.52, no.4, pp.340 - 344 | - |
dc.identifier.kciid | ART001864769 | - |
dc.identifier.scopusid | 2-s2.0-84897093750 | - |
dc.citation.endPage | 344 | - |
dc.citation.startPage | 340 | - |
dc.citation.title | JOURNAL OF MICROBIOLOGY | - |
dc.citation.volume | 52 | - |
dc.citation.number | 4 | - |
dc.contributor.affiliatedAuthor | Kang, Se Chan | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Zanthoxylum piperitum | - |
dc.subject.keywordAuthor | Rutaceae | - |
dc.subject.keywordAuthor | flavonol glycoside | - |
dc.subject.keywordAuthor | anti-influenza activity | - |
dc.subject.keywordAuthor | neuraminidase inhibitor | - |
dc.subject.keywordPlus | ALIPHATIC ACID-AMIDES | - |
dc.subject.keywordPlus | RESISTANT STAPHYLOCOCCUS-AUREUS | - |
dc.subject.keywordPlus | RAW 264.7 CELLS | - |
dc.subject.keywordPlus | INHIBITORY-ACTIVITIES | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | YOUNG LEAVES | - |
dc.subject.keywordPlus | MAP KINASE | - |
dc.subject.keywordPlus | A VIRUS | - |
dc.subject.keywordPlus | DC. | - |
dc.subject.keywordPlus | PLANTS | - |
dc.relation.journalResearchArea | Microbiology | - |
dc.relation.journalWebOfScienceCategory | Microbiology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.