Identification of Anti-cancer Active Components of Taraxacum coreanum on Human Gastric Cancer AGS Cells
DC Field | Value | Language |
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dc.contributor.author | Yamabe, Noriko | - |
dc.contributor.author | Kang, Ki Sung | - |
dc.contributor.author | Lee, Ah Young | - |
dc.contributor.author | Lee, Dahae | - |
dc.contributor.author | Choi, Ji Myung | - |
dc.contributor.author | Lee, Sullim | - |
dc.contributor.author | Park, Jun Yeon | - |
dc.contributor.author | Hwang, Gwi Seo | - |
dc.contributor.author | Kim, Hyun Young | - |
dc.contributor.author | Cho, Eun-Ju | - |
dc.contributor.author | Lee, Sanghyun | - |
dc.date.available | 2020-02-28T17:46:14Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2014-04 | - |
dc.identifier.issn | 1738-2203 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/12758 | - |
dc.description.abstract | Anti-cancer effects were compared amongst Taraxacum coreanum extract, its fractions, and 7 ingredients (beta-sitosterol, daucosterol, taraxasteryl acetate, chrysoeriol, diosmetin, luteolin, and luteoloside). Exposure to the ethyl acetate fraction (50 and 100 mu g/mL) of T. coreanum extract and luteolin (10 and 50 mu M) for 24 h induced the cleavage of poly (ADP-ribose) polymerase (PARP), caspase-3, and caspase-8, in a dose-dependent manner. These findings demonstrate that luteolin is the main active component of T. coreanum extract activating caspases-3 and -8 which contribute to apoptotic cell death. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC APPLIED BIOLOGICAL CHEMISTRY | - |
dc.relation.isPartOf | JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY | - |
dc.subject | IN-VITRO | - |
dc.subject | APOPTOSIS | - |
dc.subject | LUTEOLIN | - |
dc.subject | EXTRACT | - |
dc.subject | MODEL | - |
dc.title | Identification of Anti-cancer Active Components of Taraxacum coreanum on Human Gastric Cancer AGS Cells | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000336356900007 | - |
dc.identifier.doi | 10.1007/s13765-014-4031-2 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY, v.57, no.2, pp.187 - 190 | - |
dc.identifier.kciid | ART001868973 | - |
dc.identifier.scopusid | 2-s2.0-84899845909 | - |
dc.citation.endPage | 190 | - |
dc.citation.startPage | 187 | - |
dc.citation.title | JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY | - |
dc.citation.volume | 57 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | Yamabe, Noriko | - |
dc.contributor.affiliatedAuthor | Kang, Ki Sung | - |
dc.contributor.affiliatedAuthor | Lee, Dahae | - |
dc.contributor.affiliatedAuthor | Hwang, Gwi Seo | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | apoptosis | - |
dc.subject.keywordAuthor | caspase | - |
dc.subject.keywordAuthor | gastric cancer | - |
dc.subject.keywordAuthor | luteolin | - |
dc.subject.keywordAuthor | Taraxacum coreanum | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | APOPTOSIS | - |
dc.subject.keywordPlus | LUTEOLIN | - |
dc.subject.keywordPlus | EXTRACT | - |
dc.subject.keywordPlus | MODEL | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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