Ovalbumin으로 유발된 아토피피부염 모델 마우스에 대한 복합한약추출물 경구투여의 효과
DC Field | Value | Language |
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dc.contributor.author | 김경진 | - |
dc.contributor.author | 김경준 | - |
dc.date.available | 2020-02-28T20:42:48Z | - |
dc.date.created | 2020-02-12 | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 1738-6640 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/13541 | - |
dc.description.abstract | Objective: This study was to evaluate whether herbal mixture (HM-A : Houttuynia cordata Thunberg, Rubuscoreanus, Rehmannia glutinosa, Prunus yedoensis, HM-B : Houttuynia cordata Thunberg, Rubus coreanus,Rehmannia glutinosa, Angelica gigas nakai) supresses the development of atopic dermatitis in Balb/c micesensitized by ovalbumin. Methods: Mice were sensitized by intraperitoneal injection of ovalbumin plus aluminum hydroxide hydrate,followed by epicutaneous sensitization for 6 weeks. After induced atopic dermatitis, HM-A and HM-B were orallyadministrated for two weeks(once a two days) as a 50 mg/kg concentration. After all mice were sacrificed at theend of the experiment, skin and blood were harvested. Results: Oral administration group was reduced the infiltration of eosinophils, mast cells and total T cells on theskin areas as well as blood analysis. Also, cutaneous expression of IL-4,13,17 decreased. Blood IgE level wasdecreased. Conclusion: These drugs could be potential candidates for the atopic dermatitis. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 대한한방안이비인후피부과학회 | - |
dc.relation.isPartOf | 한방안이비인후피부과학회지 | - |
dc.title | Ovalbumin으로 유발된 아토피피부염 모델 마우스에 대한 복합한약추출물 경구투여의 효과 | - |
dc.title.alternative | Oral Administration Effects of Herbal Extracts on Atopic Dermatitis in Balb/c Mice Sensitized by Ovalbumin | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 2 | - |
dc.identifier.bibliographicCitation | 한방안이비인후피부과학회지, v.27, no.3, pp.72 - 83 | - |
dc.identifier.kciid | ART001900992 | - |
dc.citation.endPage | 83 | - |
dc.citation.startPage | 72 | - |
dc.citation.title | 한방안이비인후피부과학회지 | - |
dc.citation.volume | 27 | - |
dc.citation.number | 3 | - |
dc.contributor.affiliatedAuthor | 김경진 | - |
dc.contributor.affiliatedAuthor | 김경준 | - |
dc.subject.keywordAuthor | Atopic dermatitis | - |
dc.subject.keywordAuthor | Houttuynia cordata Thunberg | - |
dc.subject.keywordAuthor | Rubus coreanus | - |
dc.subject.keywordAuthor | Rehmannia glutinosa | - |
dc.subject.keywordAuthor | Prunus yedoensis | - |
dc.subject.keywordAuthor | Angelica gigas nakai | - |
dc.subject.keywordAuthor | Ovalbumin | - |
dc.subject.keywordAuthor | Balb/c Mice | - |
dc.description.journalRegisteredClass | kci | - |
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