황금, 인동등 추출물 혼합의 항염효능에 관한 in vitro 연구
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 하유군 | - |
dc.contributor.author | 최유경 | - |
dc.date.available | 2020-02-28T20:43:20Z | - |
dc.date.created | 2020-02-12 | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 1738-7698 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/13576 | - |
dc.description.abstract | This study aimed at examining the anti-inflammatory effects of Scutellariae Radix & Lonicerae Caulis water extract(SC). RAW 264.7 mouse macrophage cells were treated with 25∼200㎍/㎖ SC for 24 hours. Cell viability was then measured using MTT assays. The nitric oxide(NO) production and the creation of several cytokines in LPS-stimulated RAW 264.7 cells were investigated. SC inhibited significantly increasing the production of NO in LPS-induced RAW 264.7 cell at the density of 25, 50 and 200 ㎍/㎖. SC inhibited significantly the TNF-α of the RAW 264.7 cell induced by LPS at the density of 50㎍/㎖. SC inhibited significantly the MIP-1α of the RAW 264.7 cell induced by LPS at the density of 25, 50 and 100㎍/㎖. SC inhibited significantly the MIP-1β, MIP-2 at the density of 50, 100㎍/㎖ in the RAW 264.7 cell increased by LPS, respectively. SC did not affect the production levels of VEGF in RAW 264.7 cell. As a result, SC significantly inhibited the inductions of MIP-1α, MIP-1β, MIP-2 and NO in LPS-induced RAW 264.7 cell without causing the toxicity. These results signify that SC has anti-inflammatory effects on controlling the over inflammatory reaction on the RAW 264.7 cell. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 한의병리학회 | - |
dc.relation.isPartOf | 동의생리병리학회지 | - |
dc.title | 황금, 인동등 추출물 혼합의 항염효능에 관한 in vitro 연구 | - |
dc.title.alternative | Anti-inflammatory Effect of Combination of Scutellariae Radix and Lonicerae Caulis Water Extract | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 2 | - |
dc.identifier.bibliographicCitation | 동의생리병리학회지, v.28, no.3, pp.330 - 336 | - |
dc.identifier.kciid | ART001889137 | - |
dc.citation.endPage | 336 | - |
dc.citation.startPage | 330 | - |
dc.citation.title | 동의생리병리학회지 | - |
dc.citation.volume | 28 | - |
dc.citation.number | 3 | - |
dc.contributor.affiliatedAuthor | 하유군 | - |
dc.contributor.affiliatedAuthor | 최유경 | - |
dc.subject.keywordAuthor | Scutellariae Radix | - |
dc.subject.keywordAuthor | Lonicerae Caulis | - |
dc.subject.keywordAuthor | anti-inflammation | - |
dc.subject.keywordAuthor | NO | - |
dc.subject.keywordAuthor | TNF-α | - |
dc.subject.keywordAuthor | MIP-1α | - |
dc.subject.keywordAuthor | MIP-1β | - |
dc.subject.keywordAuthor | MIP-2 | - |
dc.description.journalRegisteredClass | kci | - |
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