치아우식증 유발 균주에 대한 패러다임의 변화: 생태학적 관점

Abstract

Dental plaque resides passively at a site and makes an active contribution to the maintenance of health. The bacterial composition of plaque remainsrelatively stable despite regular exposure to minor environmental stress. This stability, homeostasis is due to a dynamic balance of microbialinteractions. However, the homeostasis can break down, leading to shifts in the balance of the microflora. This change can be a sign of initial dentalcaries. It is proposed that disease can be prevented or treated not only by targeting the putative pathogens but also by interfering with the processesthat drive the breakdown in homeostasis. It is essential to understand the plaque as a mixed species biofilm. In this essay I reviewed an extensionof the caries ecological hypothesis to explain the relation between dynamic changes in the phenotypic/genotypic properties of plaque bacteria andthe demineralization and remineralization balance of the dental caries process. We will have the strategies to impact significantly on clinical practiceas understanding dental biofilm.