The Therapeutic Effects of Human Adipose-Derived Stem Cells in Alzheimer's Disease Mouse Models
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chang, Keun-A. | - |
dc.contributor.author | Kim, Hee Jin | - |
dc.contributor.author | Joo, Yuyoung | - |
dc.contributor.author | Ha, Sungji | - |
dc.contributor.author | Suh, Yoo-Hun | - |
dc.date.available | 2020-02-28T22:41:38Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2014-01 | - |
dc.identifier.issn | 1660-2854 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/14037 | - |
dc.description.abstract | Alzheimer's disease (AD) is an irreversible neurodegenerative disease, still lacking proper clinical treatment. Therefore, many researchers have focused on the possibility of therapeutic use of stem cells for AD. Adipose-derived stem cells (ASCs), mesenchymal stem cells (MSCs) isolated from adipose tissue, are well known for their pluripotency and their ability to differentiate into multiple tissue types and have immune modulatory properties similar to those of MSCs from other origins. Because of their biological properties, ASCs can be considered for cell therapy and neuroregeneration. Our recent results clearly showed the therapeutic potential of these cells after transplantation into Tg2576 mice (an AD mouse model). Intravenously or intracerebrally transplanted human ASCs (hASCs) greatly improved the memory impairment and the neuropathology, suggesting that hASCs have a high therapeutic potential for AD. (C) 2013 S. Karger AG, Basel | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KARGER | - |
dc.relation.isPartOf | NEURODEGENERATIVE DISEASES | - |
dc.title | The Therapeutic Effects of Human Adipose-Derived Stem Cells in Alzheimer's Disease Mouse Models | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000330752200012 | - |
dc.identifier.doi | 10.1159/000355261 | - |
dc.identifier.bibliographicCitation | NEURODEGENERATIVE DISEASES, v.13, no.2-3, pp.99 - 102 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-84896732245 | - |
dc.citation.endPage | 102 | - |
dc.citation.startPage | 99 | - |
dc.citation.title | NEURODEGENERATIVE DISEASES | - |
dc.citation.volume | 13 | - |
dc.citation.number | 2-3 | - |
dc.contributor.affiliatedAuthor | Chang, Keun-A. | - |
dc.contributor.affiliatedAuthor | Joo, Yuyoung | - |
dc.contributor.affiliatedAuthor | Ha, Sungji | - |
dc.type.docType | Article; Proceedings Paper | - |
dc.subject.keywordAuthor | Alzheimer&apos | - |
dc.subject.keywordAuthor | s disease | - |
dc.subject.keywordAuthor | Adipose-derived stem cells | - |
dc.subject.keywordPlus | NERVOUS-SYSTEM | - |
dc.subject.keywordPlus | STROMAL CELLS | - |
dc.subject.keywordPlus | TRANSPLANTATION | - |
dc.subject.keywordPlus | DIFFERENTIATION | - |
dc.subject.keywordPlus | TISSUE | - |
dc.subject.keywordPlus | MEMORY | - |
dc.subject.keywordPlus | BRAIN | - |
dc.subject.keywordPlus | RATS | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.