Relationship between body fat and diabetic retinopathy in patients with type 2 diabetes: a nationwide survey in Korea
DC Field | Value | Language |
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dc.contributor.author | Hwang, In Cheol | - |
dc.contributor.author | Bae, Jeong Hun | - |
dc.contributor.author | Kim, Joon Mo | - |
dc.date.available | 2020-02-27T02:42:50Z | - |
dc.date.created | 2020-02-04 | - |
dc.date.issued | 2019-06 | - |
dc.identifier.issn | 0950-222X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/1409 | - |
dc.description.abstract | Purpose To evaluate the association of body mass index (BMI), waist circumference, and body fat with diabetic retinopathy (DR) in Korean patients with type 2 diabetes. Methods Among the 1130 participants 19 years of age or older with type 2 diabetes enrolled in the nationwide survey, a total of 887 participants were included in the analyses after excluding patients with ungradable fundus images. The presence and severity of DR were graded with seven-field fundus photographs. The associations between DR and anthropometric parameters and total body fat, which was assessed by dual-energy X-ray absorptiometry, were analysed using multivariate logistic regression models. Results Patients were divided into three groups according to severity of DR: no DR (n = 702, 79.1%), mild/moderate DR (n = 130, 14.7%), and vision-threatening DR (n = 55, 6.2%). In multivariate-adjusted analyses, higher BMI (adjusted odds ratio [aOR], 0.80; 95% confidence interval [CI], 0.70-0.92; P = 0.001), larger waist circumference (aOR, 0.96; 95% CI, 0.91-1.00; P = 0.047), and higher total body fat (aOR, 0.86; 95% CI, 0.79-0.92; P < 0.001) were significantly associated with a lower risk of vision-threatening DR. In sex-stratified analyses, however, only total body fat in women showed a significant inverse association with the presence of DR (aOR, 0.93; 95% CI, 0.88-0.98; P < 0.001) and independently with the severity of DR (P for trend = 0.004). Conclusion In Korean patients with type 2 diabetes, obese patients might be less likely to have vision-threatening DR. Total body fat in women appears to be inversely and independently associated with DR prevalence and progression. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | NATURE PUBLISHING GROUP | - |
dc.relation.isPartOf | EYE | - |
dc.subject | BETA-CELL FUNCTION | - |
dc.subject | RISK-FACTORS | - |
dc.subject | MASS INDEX | - |
dc.subject | ABDOMINAL OBESITY | - |
dc.subject | ADIPONECTIN | - |
dc.subject | PREVALENCE | - |
dc.subject | ASSOCIATION | - |
dc.subject | GLUCOSE | - |
dc.subject | PEOPLE | - |
dc.subject | AGE | - |
dc.title | Relationship between body fat and diabetic retinopathy in patients with type 2 diabetes: a nationwide survey in Korea | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000470242200021 | - |
dc.identifier.doi | 10.1038/s41433-019-0352-z | - |
dc.identifier.bibliographicCitation | EYE, v.33, no.6, pp.980 - 987 | - |
dc.identifier.scopusid | 2-s2.0-85061486448 | - |
dc.citation.endPage | 987 | - |
dc.citation.startPage | 980 | - |
dc.citation.title | EYE | - |
dc.citation.volume | 33 | - |
dc.citation.number | 6 | - |
dc.contributor.affiliatedAuthor | Hwang, In Cheol | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | BETA-CELL FUNCTION | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | MASS INDEX | - |
dc.subject.keywordPlus | ABDOMINAL OBESITY | - |
dc.subject.keywordPlus | ADIPONECTIN | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | GLUCOSE | - |
dc.subject.keywordPlus | PEOPLE | - |
dc.subject.keywordPlus | AGE | - |
dc.relation.journalResearchArea | Ophthalmology | - |
dc.relation.journalWebOfScienceCategory | Ophthalmology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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