Characteristics of Anemia and Iron Deficiency After Kidney Transplant
DC Field | Value | Language |
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dc.contributor.author | Jeong, Jong Cheol | - |
dc.contributor.author | Ro, Han | - |
dc.contributor.author | Yang, Jaeseok | - |
dc.contributor.author | Huh, Kyu Ha | - |
dc.contributor.author | Park, Jae Berm | - |
dc.contributor.author | Cho, Jang-Hee | - |
dc.contributor.author | Lee, Sik | - |
dc.contributor.author | Han, Seung-Yeup | - |
dc.contributor.author | Ahn, Curie | - |
dc.date.available | 2020-02-27T02:42:57Z | - |
dc.date.created | 2020-02-04 | - |
dc.date.issued | 2019-06 | - |
dc.identifier.issn | 0041-1345 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/1419 | - |
dc.description.abstract | Background. Numerous studies have shown that iron deficiency is common in patients with end-stage renal disease. However, change of iron deficiency after kidney transplant (KT) is not fully understood. This study was undertaken to examine sequential changes of iron level after KT. Methods. A total of 1080 KT recipients enrolled in a multicenter observational cohort study between July 2012 and August 2018. A total of 786 patients with transferrin saturation and ferritin level at pretransplant and 1 year after KT were reviewed. Iron deficiency was defined as ferritin <200 ng/mL and total saturation of transferrin (TSAT) < 20%. Anemia was defined as hemoglobin (Hb) < 13 g/dL (male) or <12 g/dL (female). Results. Hemoglobin at 1 year after KT was higher than Hb at KT (13.64 [SD, 1.87] g/dL vs 10.53 [SD, 1.63] g/dL; P <.001). The TSAT decreased from baseline at 1 year after KT (33.89% [SD, 18.73%] vs 29.09% [SD, 14.54%]; P <.001), and ferritin level decreased from baseline at 1 year (190.63 [SD, 217.43] ng/mL vs 141.39 [194.25] ng/mL; P <.001). In patients with anemia at pretransplant, the group with anemia at 1 year after KT (persistent group) and the group without anemia at 1 year after KT (improved group) were compared. The persistent group showed higher pretransplant TSAT, lower 1-year TSAT, and lower estimated glomerular filtration rate at 1 year after KT than the improved group. In multivariate analysis, low ferritin at KT, low TSAT at 1 year, and high ferritin at 1 year were the risk factors for low Hb level at 1 year after adjusting multiple variables. Conclusion. Anemia improved within 1 year after KT, although patients with iron deficiency increased. While ferritin reflected the inflammatory status, low TSAT at 1 year after KT was a risk factor for anemia at 1 year after KT. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.relation.isPartOf | TRANSPLANTATION PROCEEDINGS | - |
dc.subject | RISK-FACTORS | - |
dc.title | Characteristics of Anemia and Iron Deficiency After Kidney Transplant | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000471836700023 | - |
dc.identifier.doi | 10.1016/j.transproceed.2019.01.140 | - |
dc.identifier.bibliographicCitation | TRANSPLANTATION PROCEEDINGS, v.51, no.5, pp.1406 - 1409 | - |
dc.identifier.scopusid | 2-s2.0-85065015546 | - |
dc.citation.endPage | 1409 | - |
dc.citation.startPage | 1406 | - |
dc.citation.title | TRANSPLANTATION PROCEEDINGS | - |
dc.citation.volume | 51 | - |
dc.citation.number | 5 | - |
dc.contributor.affiliatedAuthor | Ro, Han | - |
dc.type.docType | Article; Proceedings Paper | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalResearchArea | Transplantation | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.relation.journalWebOfScienceCategory | Transplantation | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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