Living donor and recipient screening for latent tuberculosis infection by tuberculin skin test and interferon-gamma releasing assay in a country with an intermediate burden of tuberculosis
DC Field | Value | Language |
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dc.contributor.author | Moon, Song Mi | - |
dc.contributor.author | Park, In-Ah | - |
dc.contributor.author | Kim, Sun-Mi | - |
dc.contributor.author | Park, Su-Jin | - |
dc.contributor.author | Jung, Joo Hee | - |
dc.contributor.author | Kim, Young Hoon | - |
dc.contributor.author | Park, Jae Berm | - |
dc.contributor.author | Hong, Bumsik | - |
dc.contributor.author | Lee, Sang-Oh | - |
dc.contributor.author | Choi, Sang-Ho | - |
dc.contributor.author | Kim, Yang Soo | - |
dc.contributor.author | Woo, Jun Hee | - |
dc.contributor.author | Park, Su-Kil | - |
dc.contributor.author | Lee, Sang Koo | - |
dc.contributor.author | Park, Jung Sik | - |
dc.contributor.author | Han, Duck Jong | - |
dc.contributor.author | Kim, Sung-Han | - |
dc.date.available | 2020-02-28T22:46:10Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2013-10 | - |
dc.identifier.issn | 1341-321X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/14268 | - |
dc.description.abstract | There are few data on donor screening for latent tuberculosis infection (LTBI) using the tuberculin skin test (TST) and interferon-gamma releasing assay (IGRA). In South Korea, most renal allografts involve living donors (average, 80 %). Hence, we have an opportunity to evaluate donor and recipient screening for LTBI by TST and IGRA. All donors and recipients admitted for kidney transplantation during a 20-month period were evaluated prospectively by using TST and Mycobacterium tuberculosis-specific enzyme-linked immunosorbent spot (ELISPOT) assay. The study population consisted of 205 living donor-recipient pairs (a parts per thousand yen16 years) including 15 (7 %) who yielded indeterminate donor or recipient ELISPOT results. Of the 205 donors, 63 (31 %) gave a positive TST a parts per thousand yen5 mm, 33 (16 %) a positive TST a parts per thousand yen10 mm, and 96 (47 %) a positive ELISPOT. Of the 205 recipients, 9 (5 %) gave a positive TST a parts per thousand yen5 mm, 3 (2 %) a positive TST a parts per thousand yen10 mm, and 79 (39 %) had a positive ELISPOT. Of the 205 donor-recipient pairs, only 59 (29 %) gave negative donor and recipient ELISPOT results and 139 (68 %) negative donor and recipient TSTs (< 5 mm) (P < 0.001). One third of donor-recipient pairs tends to be positive in the TST, and two thirds of the donor-recipient pairs tends to be positive in the ELISPOT. Given the high positive rate of LTBI obtained by screening donors, further studies on the clinical value of solid organ transplant donors with positive TST or ELISPOT and health economics analysis in countries with intermediate burden of TB are needed for policy decisions on isoniazid (INH) prophylaxis. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER JAPAN KK | - |
dc.relation.isPartOf | JOURNAL OF INFECTION AND CHEMOTHERAPY | - |
dc.subject | CELL-BASED ASSAY | - |
dc.subject | TRANSPLANT RECIPIENTS | - |
dc.subject | DIAGNOSTIC USEFULNESS | - |
dc.title | Living donor and recipient screening for latent tuberculosis infection by tuberculin skin test and interferon-gamma releasing assay in a country with an intermediate burden of tuberculosis | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000325623900040 | - |
dc.identifier.doi | 10.1007/s10156-013-0578-9 | - |
dc.identifier.bibliographicCitation | JOURNAL OF INFECTION AND CHEMOTHERAPY, v.19, no.5, pp.1009 - 1013 | - |
dc.identifier.scopusid | 2-s2.0-84885950197 | - |
dc.citation.endPage | 1013 | - |
dc.citation.startPage | 1009 | - |
dc.citation.title | JOURNAL OF INFECTION AND CHEMOTHERAPY | - |
dc.citation.volume | 19 | - |
dc.citation.number | 5 | - |
dc.contributor.affiliatedAuthor | Moon, Song Mi | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Tuberculosis | - |
dc.subject.keywordAuthor | Tuberculin skin test | - |
dc.subject.keywordAuthor | ELISPOT | - |
dc.subject.keywordAuthor | Kidney transplantation | - |
dc.subject.keywordPlus | CELL-BASED ASSAY | - |
dc.subject.keywordPlus | TRANSPLANT RECIPIENTS | - |
dc.subject.keywordPlus | DIAGNOSTIC USEFULNESS | - |
dc.relation.journalResearchArea | Infectious Diseases | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Infectious Diseases | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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