Effects of high positive end-expiratory pressure on haemodynamics and cerebral oxygenation during pneumoperitoneum in the Trendelenburg position
- Authors
- Jo, Y. Y.; Lee, J. Y.; Lee, M. G.; Kwak, H. J.
- Issue Date
- Sep-2013
- Publisher
- WILEY-BLACKWELL
- Citation
- ANAESTHESIA, v.68, no.9, pp.938 - 943
- Journal Title
- ANAESTHESIA
- Volume
- 68
- Number
- 9
- Start Page
- 938
- End Page
- 943
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/14343
- DOI
- 10.1111/anae.12284
- ISSN
- 0003-2409
- Abstract
- We investigated the effects of 10cmH(2)O positive end-expiratory pressure on cerebral haemodynamics and cerebral oxygenation in patients undergoing laparoscopic lower abdominal surgery in the 30 degrees Trendelenburg position during desflurane anaesthesia. Twenty-six patients were enrolled in this study. After anaesthesia induction, pneumoperitoneum was applied in Trendelenburg position. Twenty minutes later, positive end-expiratory pressure was applied. There was no change in regional cerebral oxygen saturation (p=0.376). Cerebral perfusion pressure decreased significantly over time (p<0.001) and positive end-expiratory pressure caused a further decrease in cerebral perfusion pressure (p=0.036). The application of 10cmH(2)O positive end-expiratory pressure during pneumoperitoneum in the Trendelenburg position preserved regional cerebral oxygen saturation, but cerebral perfusion pressure decreased significantly due to its secondary haemodynamic effects.
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