Effects of beta-glucans from Coriolus versicolor on macrophage phagocytosis are related to the Akt and CK2/Ikaros
DC Field | Value | Language |
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dc.contributor.author | Kang, Se Chan | - |
dc.contributor.author | Koo, Hyun Jung | - |
dc.contributor.author | Park, Sulkyung | - |
dc.contributor.author | Lim, Jung Dae | - |
dc.contributor.author | Kim, Ye-Jin | - |
dc.contributor.author | Kim, Taeseong | - |
dc.contributor.author | Namkoong, Seung | - |
dc.contributor.author | Jang, Ki-Hyo | - |
dc.contributor.author | Pyo, Suhkneung | - |
dc.contributor.author | Jang, Seon-A | - |
dc.contributor.author | Sohn, Eun-Hwa | - |
dc.date.available | 2020-02-28T23:45:43Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2013-06 | - |
dc.identifier.issn | 0141-8130 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/14505 | - |
dc.description.abstract | Coriolus versicolor has been known to be an immune stimulator effects. For further understanding of the phagocytic activity and the intracellular mechanisms of beta-glucan from C versicolor (CVG), we examined the phagocytic activity, phosphorylation of Akt and CK2, nucleus translocation of p65 and Ikaros activity in beta-glucan-treated macrophages using RT-PCR, western blotting, and IP assay. The role of Ikaros in regulating phagocytic effects of CVG was also determined using Ikaros dominant negative isoform cells. This study suggests that CIC2/Ikaros are positive regulators and novel signaling pathway involved in phagocytosis and contributes to elucidating the mechanism underlying phagocytic activity induced by beta-glucan. (C) 2013 Elsevier B.V. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | - |
dc.subject | PROTEIN-KINASE CK2 | - |
dc.subject | NECROSIS-FACTOR-ALPHA | - |
dc.subject | INFLAMMATORY RESPONSES | - |
dc.subject | MEDIATED PHAGOCYTOSIS | - |
dc.subject | DECTIN-1 | - |
dc.subject | RECEPTOR | - |
dc.subject | PHOSPHORYLATION | - |
dc.subject | RECOGNITION | - |
dc.subject | ACTIVATION | - |
dc.subject | IKAROS | - |
dc.title | Effects of beta-glucans from Coriolus versicolor on macrophage phagocytosis are related to the Akt and CK2/Ikaros | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000319098900002 | - |
dc.identifier.doi | 10.1016/j.ijbiomac.2013.03.017 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, v.57, pp.9 - 16 | - |
dc.identifier.scopusid | 2-s2.0-84875494382 | - |
dc.citation.endPage | 16 | - |
dc.citation.startPage | 9 | - |
dc.citation.title | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | - |
dc.citation.volume | 57 | - |
dc.contributor.affiliatedAuthor | Kang, Se Chan | - |
dc.contributor.affiliatedAuthor | Koo, Hyun Jung | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Beta-glucan | - |
dc.subject.keywordAuthor | Coriolus versicolor | - |
dc.subject.keywordAuthor | Dectin-1 | - |
dc.subject.keywordAuthor | Phagocytic activity | - |
dc.subject.keywordAuthor | RAW264.7 | - |
dc.subject.keywordPlus | PROTEIN-KINASE CK2 | - |
dc.subject.keywordPlus | NECROSIS-FACTOR-ALPHA | - |
dc.subject.keywordPlus | INFLAMMATORY RESPONSES | - |
dc.subject.keywordPlus | MEDIATED PHAGOCYTOSIS | - |
dc.subject.keywordPlus | DECTIN-1 | - |
dc.subject.keywordPlus | RECEPTOR | - |
dc.subject.keywordPlus | PHOSPHORYLATION | - |
dc.subject.keywordPlus | RECOGNITION | - |
dc.subject.keywordPlus | ACTIVATION | - |
dc.subject.keywordPlus | IKAROS | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Polymer Science | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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