Lanostane Triterpenoids from the Mushroom Naematoloma fasciculare
DC Field | Value | Language |
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dc.contributor.author | Kim, Ki Hyun | - |
dc.contributor.author | Moon, Eunjung | - |
dc.contributor.author | Choi, Sang Un | - |
dc.contributor.author | Kim, Sun Yeou | - |
dc.contributor.author | Lee, Kang Ro | - |
dc.date.available | 2020-02-28T23:47:45Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2013-05 | - |
dc.identifier.issn | 0163-3864 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/14593 | - |
dc.description.abstract | In our continuing search for structurally interesting and bioactive metabolites from Korean wild mushrooms, bioassay-guided fractionation and a chemical investigation of the MeOH extracts of the fruiting bodies of the mushroom Naematoloma fasciculare resulted in the isolation of four new lanostane triterpenoids (1-4), together with 11 known compounds (5-15). The structures of 1-5 were determined by a combination of ID and 2D NMR and HRMS. The absolute configuration of the 3-hydroxy-3-methylglutaryl group as a side chain in 1 and 2 was determined by the alkaline methanolysis method. The full NMR data assignment of the known compound fasciculol G (S) is reported for the first time. Compounds 1-15 were tested for their antiproliferative activities against four human cancer cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15) and evaluated for their inhibitory effects on nitric oxide production in a lipopolysaccharide-activated murine microglial cell line. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.relation.isPartOf | JOURNAL OF NATURAL PRODUCTS | - |
dc.subject | BIOLOGICALLY-ACTIVE SUBSTANCES | - |
dc.subject | MACROLEPIOTA-NEOMASTOIDEA | - |
dc.subject | NEAMATOLOMA-FASCICULARE | - |
dc.subject | FRUIT BODIES | - |
dc.subject | ACID MOIETY | - |
dc.subject | CYTOTOXICITY | - |
dc.subject | SESQUITERPENOIDS | - |
dc.subject | CONSTITUENTS | - |
dc.subject | METABOLITES | - |
dc.title | Lanostane Triterpenoids from the Mushroom Naematoloma fasciculare | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000319650600005 | - |
dc.identifier.doi | 10.1021/np300801x | - |
dc.identifier.bibliographicCitation | JOURNAL OF NATURAL PRODUCTS, v.76, no.5, pp.845 - 851 | - |
dc.identifier.scopusid | 2-s2.0-84878263659 | - |
dc.citation.endPage | 851 | - |
dc.citation.startPage | 845 | - |
dc.citation.title | JOURNAL OF NATURAL PRODUCTS | - |
dc.citation.volume | 76 | - |
dc.citation.number | 5 | - |
dc.contributor.affiliatedAuthor | Kim, Sun Yeou | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | BIOLOGICALLY-ACTIVE SUBSTANCES | - |
dc.subject.keywordPlus | MACROLEPIOTA-NEOMASTOIDEA | - |
dc.subject.keywordPlus | NEAMATOLOMA-FASCICULARE | - |
dc.subject.keywordPlus | FRUIT BODIES | - |
dc.subject.keywordPlus | ACID MOIETY | - |
dc.subject.keywordPlus | CYTOTOXICITY | - |
dc.subject.keywordPlus | SESQUITERPENOIDS | - |
dc.subject.keywordPlus | CONSTITUENTS | - |
dc.subject.keywordPlus | METABOLITES | - |
dc.relation.journalResearchArea | Plant Sciences | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Plant Sciences | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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