Expression of Autoantibodies in Patients With Sudden Sensorineural Hearing Loss
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cho, Chang Hyun | - |
dc.contributor.author | Jung, Byoung Seo | - |
dc.contributor.author | Jung, Joo Hyun | - |
dc.contributor.author | Lee, Jung Ho | - |
dc.contributor.author | Lee, Ju Hyoung | - |
dc.date.available | 2020-02-29T00:45:32Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2013-02 | - |
dc.identifier.issn | 0003-4894 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/14805 | - |
dc.description.abstract | Objectives: The aim of this study was to establish the expression rate of autoimmunity in patients with sudden sensorineural hearing loss and to determine whether a positive marker is associated with a higher rate of hearing recovery after steroid treatment. Methods: A prospective study was performed on 137 patients who experienced sudden sensorineural hearing loss and underwent immunoserologic investigations. Autoantibodies evaluated on the day of admission included anti-double-stranded DNA, rheumatoid factor, antiphospholipid immunoglobulins G and M, antinuclear antibody, and complements C3 and C4. Results: Of 137 patients, 75 were male and 62 were female (mean age, 45.1 years). Hearing loss was found on the left side in 61 patients and on the right side in 76 patients. Elevation of at least 1 autoantibody or abnormal complement levels were found in 80 patients (58%), and abnormalities of 2 or more antibodies were found in 28 (20%). There were no statistically significant correlations between autoantibody abnormalities and age, initial hearing level, or positive treatment response. Conclusions: There is no clear evidence of a correlation between autoimmunity and hearing improvement in patients with autoantibody abnormalities. A high (but not significant) expression rate of autoantibody abnormality and complement level was seen in patients with sudden sensorineural hearing loss. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ANNALS PUBL CO | - |
dc.relation.isPartOf | ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY | - |
dc.subject | INNER-EAR DISEASE | - |
dc.subject | MENIERES-DISEASE | - |
dc.subject | AUTOANTIGEN | - |
dc.subject | DISORDERS | - |
dc.title | Expression of Autoantibodies in Patients With Sudden Sensorineural Hearing Loss | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000323094100009 | - |
dc.identifier.doi | 10.1177/000348941312200209 | - |
dc.identifier.bibliographicCitation | ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, v.122, no.2, pp.131 - 134 | - |
dc.identifier.scopusid | 2-s2.0-84873692844 | - |
dc.citation.endPage | 134 | - |
dc.citation.startPage | 131 | - |
dc.citation.title | ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY | - |
dc.citation.volume | 122 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | Cho, Chang Hyun | - |
dc.contributor.affiliatedAuthor | Jung, Byoung Seo | - |
dc.contributor.affiliatedAuthor | Jung, Joo Hyun | - |
dc.contributor.affiliatedAuthor | Lee, Jung Ho | - |
dc.contributor.affiliatedAuthor | Lee, Ju Hyoung | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | autoantibody | - |
dc.subject.keywordAuthor | corticosteroid | - |
dc.subject.keywordAuthor | sudden sensorineural hearing loss | - |
dc.subject.keywordPlus | INNER-EAR DISEASE | - |
dc.subject.keywordPlus | MENIERES-DISEASE | - |
dc.subject.keywordPlus | AUTOANTIGEN | - |
dc.subject.keywordPlus | DISORDERS | - |
dc.relation.journalResearchArea | Otorhinolaryngology | - |
dc.relation.journalWebOfScienceCategory | Otorhinolaryngology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.