黃連 추출물이 대식세포의 면역단백질 생성에 미치는 영향
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김복기 | - |
dc.contributor.author | 한효상 | - |
dc.contributor.author | 이영종 | - |
dc.date.available | 2020-02-29T01:45:27Z | - |
dc.date.created | 2020-02-12 | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 1229-1218 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/15155 | - |
dc.description.abstract | Objectives : The purpose of this study is to observe the effect of Coptidis Rhizoma (CCE-extract of C. chinensis Rhizome) in induction of immune protein on mouse macrophages. Methods : To analyze cytokines interleukin(IL)-1α, IL-3, IL-9, IL-12p40, IL-13, IL-17, Monocyte Chemoattractant Protein(MCP)-1 induced by macrophages, mouse macrophages were incubated with CCE and was measured. Results : IL-1α measurement, CCE showed significant inhibition only at concentration level of 200 ㎍/mL. IL-3, MCP-1 measurement, CCE showed significant inhibition only at concentration level of 100, 200 ㎍/mL. IL-9 measurement, CCE showed significant inhibition only at concentration level of 50 ㎍/mL. IL-13 measurement, CCE showed significant inhibition only at concentration level of 50, 100, 200 ㎍/mL. The IL-12p40, IL-17 levels indicated no changes at 25, 50, 100, 200 ㎍/mL on mouse macrophages. Conclusions : CCE did not significantly increased inflammatory cytokines IL-1α, IL-3, IL-9, IL-12p40, IL-13, IL-17, Monocyte Chemoattractant Protein(MCP)-1 on mouse macrophages. It was verified CCE does not trigger cytokine related hypersensitivity reaction of organism or exacerbation of acute/chronic inflammatory disease. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 대한한의학방제학회 | - |
dc.relation.isPartOf | 대한한의학 방제학회지 | - |
dc.title | 黃連 추출물이 대식세포의 면역단백질 생성에 미치는 영향 | - |
dc.title.alternative | Effect of Coptidis Rhizoma Extract on Cytokine Production of Mouse Macrophages | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 2 | - |
dc.identifier.doi | 10.14374/HFS.2013.21.2.081 | - |
dc.identifier.bibliographicCitation | 대한한의학 방제학회지, v.21, no.2, pp.81 - 89 | - |
dc.identifier.kciid | ART001829471 | - |
dc.citation.endPage | 89 | - |
dc.citation.startPage | 81 | - |
dc.citation.title | 대한한의학 방제학회지 | - |
dc.citation.volume | 21 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | 김복기 | - |
dc.contributor.affiliatedAuthor | 이영종 | - |
dc.subject.keywordAuthor | Coptidis Rhizoma | - |
dc.subject.keywordAuthor | Macrophage | - |
dc.subject.keywordAuthor | Cyokine | - |
dc.subject.keywordAuthor | Interleukin-1α | - |
dc.subject.keywordAuthor | Interleukin-17 | - |
dc.description.journalRegisteredClass | kci | - |
dc.description.journalRegisteredClass | other | - |
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