LPS로 유발된 마우스 대식세포의 케모카인류 염증인자 생성에 미치는 백삼이중탕 및 홍삼이중탕의 영향비교
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박완수 | - |
dc.date.available | 2020-02-29T01:45:42Z | - |
dc.date.created | 2020-02-12 | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 1738-7698 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/15168 | - |
dc.description.abstract | The purpose of this study is to investigate effects of White Ginseng-Ejung-tang (EG) and Red Ginseng-Ejung-tang (ER) water extract on production of various cytokines such as interleukin (IL)-21, IL-25, IL-28β, erythropoietin (EPO), Exodus-2, monocyte chemotactic protein (MCP)-5, macrophage inflammatory protein (MIP)-3α, MIP-3β, Fractalkine, and TARC in RAW 264.7 mouse macrophages stimulated by lipopolysaccharide (LPS). Levels of cytokines were measured by High-throughput multiplex bead array cytokine assay based on xMAP (multi-analyte profiling beads) technology. ER significantly decreased levels of IL-21, IL-25, IL-28β, EPO, Exodus-2, MCP-5, MIP-3α, MIP-3β, TARC, and fractalkine for 24 h incubation at the oncentrations of 25 and 100 ㎍/mL in LPS-induced RAW 264.7 (P < 0.05). But EG did not show any significant effect. These results suggest that ER has anti-inflammtory property related with its inhibition on the production of IL-21, IL-25, IL-28β, and chemokines such as EPO, MCP-5, MIP-3α, MIP-3β, Fractalkine, Exodus-2, and TARC in LPS-induced macrophages. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 한의병리학회 | - |
dc.relation.isPartOf | 동의생리병리학회지 | - |
dc.title | LPS로 유발된 마우스 대식세포의 케모카인류 염증인자 생성에 미치는 백삼이중탕 및 홍삼이중탕의 영향비교 | - |
dc.title.alternative | Effect of White Ginseng-Ejung-tang and Red Ginseng-Ejung-tang Water Extract on Production of Chemokines and IL-21 in LPS-induced RAW 264.7 Mouse Macrophages | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 2 | - |
dc.identifier.bibliographicCitation | 동의생리병리학회지, v.27, no.6, pp.795 - 801 | - |
dc.identifier.kciid | ART001831053 | - |
dc.citation.endPage | 801 | - |
dc.citation.startPage | 795 | - |
dc.citation.title | 동의생리병리학회지 | - |
dc.citation.volume | 27 | - |
dc.citation.number | 6 | - |
dc.contributor.affiliatedAuthor | 박완수 | - |
dc.subject.keywordAuthor | White Ginseng | - |
dc.subject.keywordAuthor | Red Ginseng | - |
dc.subject.keywordAuthor | Ejung-tang | - |
dc.subject.keywordAuthor | Macrophage | - |
dc.subject.keywordAuthor | Inflammation | - |
dc.subject.keywordAuthor | Interleukin | - |
dc.subject.keywordAuthor | Chemokine | - |
dc.description.journalRegisteredClass | kci | - |
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