Waldeyer's ring marginal zone B cell lymphoma: are the clinical and prognostic features nodal or extranodal? A study by the Consortium for Improving Survival of Lymphoma (CISL)
- Authors
- Oh, Sung Yong; Kim, Won Seog; Kim, Jin Seok; Kim, Seok Jin; Lee, Suee; Lee, Dae Ho; Lee, Soon Il; Kang, Hye Jin; Choi, Chul Won; Park, Jinny; Song, Moo Kon; Kim, Hyo Jung; Kwon, Jung Hye; Kwak, Jae-Yong; Bae, Sung Hwa; Park, Byeong-Bae; Do, Young-Rok; Lee, Ho Sup; Jeong, Seong Hyun; Suh, Cheolwon; Kim, Hyo-Jin
- Issue Date
- Nov-2012
- Publisher
- SPRINGER JAPAN KK
- Keywords
- Waldeyer' s ring; Marginal zone; Lymphoma
- Citation
- INTERNATIONAL JOURNAL OF HEMATOLOGY, v.96, no.5, pp.631 - 637
- Journal Title
- INTERNATIONAL JOURNAL OF HEMATOLOGY
- Volume
- 96
- Number
- 5
- Start Page
- 631
- End Page
- 637
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/16035
- DOI
- 10.1007/s12185-012-1200-0
- ISSN
- 0925-5710
- Abstract
- There has been controversy surrounding Waldeyer's ring (WR), especially focused on the question of whether it should be regarded as a nodal or an extranodal site. We conducted retrospective analyses of marginal zone B cell lymphomas involving WR (WR-MZLs) to observe their clinical features and prognosis, with specific regard to the nodal-or-extranodal question. A total of 52 patients with histological diagnosis of WR-MZL were retrospectively analyzed. The most common involvement site was the tonsil (40.4 %). Ann Arbor stage III/VI disease was present in 48.1 % (25 of 52). The response rate of the 27 stage I/II patients was 88.9 %, with 21 complete remissions and three partial remissions. The median time to progression (TTP) was 3.7 years (95 % CI 2.5-4.9 years). The estimated 5-year TTP and overall survival rates were 39.4 and 90.5 %, respectively. In a comparison with the historical data regarding extra-WR MALT lymphoma and nodal MZL (N-MZL), MALT lymphoma showed better TTP results than did WR-MZL and N-MZL (P < 0.001).
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 의과대학 > 의학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/16035)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.