Sphingolipids, Lipotoxic Cardiomyopathy, and Cardiac Failure
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Tae-Sik | - |
dc.contributor.author | Goldberg, Ira J. | - |
dc.date.available | 2020-02-29T05:42:11Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2012-10 | - |
dc.identifier.issn | 1551-7136 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/16134 | - |
dc.description.abstract | In the setting of obesity and type 2 diabetes mellitus, the ectopic disposition of lipids may be a cause of heart failure. Clinical studies have clearly shown a correlation between the accumulation of triglycerides and heart dysfunction. In this process, it is likely that there are also changes in the contents of sphingolipids. Sphingolipids are important structural and signaling molecules. One specific sphingolipid, ceramide, may cause cardiac dysfunction, whereas another, sphingosine 1-phosphate, is cardioprotective. In this review, the authors focus on the role of sphingolipids in the development and prevention of cardiac failure. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.relation.isPartOf | HEART FAILURE CLINICS | - |
dc.subject | ISCHEMIA-REPERFUSION INJURY | - |
dc.subject | INDUCED INSULIN-RESISTANCE | - |
dc.subject | PPAR-ALPHA | - |
dc.subject | LIPOPROTEIN-LIPASE | - |
dc.subject | SPHINGOSINE 1-PHOSPHATE | - |
dc.subject | DIABETIC CARDIOMYOPATHY | - |
dc.subject | CERAMIDE SYNTHESIS | - |
dc.subject | FATTY-ACIDS | - |
dc.subject | MYOCARDIAL-INFARCTION | - |
dc.subject | GLUCOSE-METABOLISM | - |
dc.title | Sphingolipids, Lipotoxic Cardiomyopathy, and Cardiac Failure | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000310397100013 | - |
dc.identifier.doi | 10.1016/j.hfc.2012.06.003 | - |
dc.identifier.bibliographicCitation | HEART FAILURE CLINICS, v.8, no.4, pp.633 - + | - |
dc.identifier.scopusid | 2-s2.0-84866598990 | - |
dc.citation.endPage | + | - |
dc.citation.startPage | 633 | - |
dc.citation.title | HEART FAILURE CLINICS | - |
dc.citation.volume | 8 | - |
dc.citation.number | 4 | - |
dc.contributor.affiliatedAuthor | Park, Tae-Sik | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Ceramide | - |
dc.subject.keywordAuthor | Cardiomyopathy | - |
dc.subject.keywordAuthor | Diabetes | - |
dc.subject.keywordAuthor | Ischemia | - |
dc.subject.keywordAuthor | Sphingosine 1-phosphate | - |
dc.subject.keywordPlus | ISCHEMIA-REPERFUSION INJURY | - |
dc.subject.keywordPlus | INDUCED INSULIN-RESISTANCE | - |
dc.subject.keywordPlus | PPAR-ALPHA | - |
dc.subject.keywordPlus | LIPOPROTEIN-LIPASE | - |
dc.subject.keywordPlus | SPHINGOSINE 1-PHOSPHATE | - |
dc.subject.keywordPlus | DIABETIC CARDIOMYOPATHY | - |
dc.subject.keywordPlus | CERAMIDE SYNTHESIS | - |
dc.subject.keywordPlus | FATTY-ACIDS | - |
dc.subject.keywordPlus | MYOCARDIAL-INFARCTION | - |
dc.subject.keywordPlus | GLUCOSE-METABOLISM | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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