Impact of Positive Peri-Stent Vascular Remodeling After Sirolimus-Eluting and Paclitaxel-Eluting Stent Implantation on 5-Year Clinical Outcomes - Intravascular Ultrasound Analysis From the Poststent Optimal Stent Expansion Trial Multicenter Randomized Trial
DC Field | Value | Language |
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dc.contributor.author | Kang, Ki-Woon | - |
dc.contributor.author | Ko, Young-Guk | - |
dc.contributor.author | Shin, Dong-Ho | - |
dc.contributor.author | Kim, Jung-Sun | - |
dc.contributor.author | Kim, Byeong-Keuk | - |
dc.contributor.author | Choi, Donghoon | - |
dc.contributor.author | Hong, Myeong-Ki | - |
dc.contributor.author | Kang, Woong Chol | - |
dc.contributor.author | Ahn, Taehoon | - |
dc.contributor.author | Jeon, Dong Woon | - |
dc.contributor.author | Yang, Joo-Young | - |
dc.contributor.author | Jang, Yangsoo | - |
dc.date.available | 2020-02-29T05:49:21Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2012-05 | - |
dc.identifier.issn | 1346-9843 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/16406 | - |
dc.description.abstract | Background: Positive peri-stent vascular remodeling (PPVR) after drug-eluting stent (DES) implantation is an important mechanism of late-acquired stent malapposition (LASM). Methods and Results: A total of 226 patients (sirolimus-eluting stent [SES], n=105; paclitaxel-eluting stent [PES], n=121) from the Poststent Optimal Stent Expansion Trial who underwent a post-intervention and 9-month follow-up intravascular ultrasound were followed clinically for 5 years. PPVR was arbitrarily defined as a >10% increase in the external elastic membrane volume index at follow-up. PPVR and LASM occurred more frequently with SESs than with PESs. The 5-year rate of major adverse cardiac events was lower with SES than with PES (10.7% vs. 23.2%, P=0.002). The late and very late stent thrombosis (ST) rate was similar between the 2 DES types, but it was higher in patients with PPVR than in those without PPVR (8.8% vs. 1.3%,-P=0.009) regardless of the DES type. Early discontinuation (<1 year) of dual antiplatelet therapy (DAPT; hazard ratio [HR], 24.14; 95% confidence interval [Cl]: 4.90-118.87; P<0.001), PPVR (HR, 14.94; 95%CI: 1.85-120.46; P=0.011), LASM (HR, 8.01; 95%CI: 1.93-33.16; P=0.004), and stent length (HR, 1.14; 95%CI: 0.98-1.32 per mm; P=0.078) were associated with increased risk of late and very late ST. Conclusions: PPVR and LASM development after DES implantation, along with early discontinuation of DAPT and longer stent length, are important risk factors of late and very late ST. (Circ J 2012; 76: 1102-1108) | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | JAPANESE CIRCULATION SOC | - |
dc.relation.isPartOf | CIRCULATION JOURNAL | - |
dc.subject | BARE-METAL STENTS | - |
dc.subject | ELEVATION MYOCARDIAL-INFARCTION | - |
dc.subject | OPTICAL COHERENCE TOMOGRAPHY | - |
dc.subject | TERM-FOLLOW-UP | - |
dc.subject | BALLOON DILATION | - |
dc.subject | ENDEAVOR-III | - |
dc.subject | MALAPPOSITION | - |
dc.subject | APPOSITION | - |
dc.subject | THROMBOSIS | - |
dc.subject | INTERVENTION | - |
dc.title | Impact of Positive Peri-Stent Vascular Remodeling After Sirolimus-Eluting and Paclitaxel-Eluting Stent Implantation on 5-Year Clinical Outcomes - Intravascular Ultrasound Analysis From the Poststent Optimal Stent Expansion Trial Multicenter Randomized Trial | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000303369800011 | - |
dc.identifier.doi | 10.1253/circj.CJ-11-1313 | - |
dc.identifier.bibliographicCitation | CIRCULATION JOURNAL, v.76, no.5, pp.1102 - 1108 | - |
dc.identifier.scopusid | 2-s2.0-84860142259 | - |
dc.citation.endPage | 1108 | - |
dc.citation.startPage | 1102 | - |
dc.citation.title | CIRCULATION JOURNAL | - |
dc.citation.volume | 76 | - |
dc.citation.number | 5 | - |
dc.contributor.affiliatedAuthor | Kang, Woong Chol | - |
dc.contributor.affiliatedAuthor | Ahn, Taehoon | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Coronary artery disease | - |
dc.subject.keywordAuthor | Drug-eluting stent | - |
dc.subject.keywordAuthor | Late and very late stent thrombosis | - |
dc.subject.keywordAuthor | Vascular remodeling | - |
dc.subject.keywordPlus | BARE-METAL STENTS | - |
dc.subject.keywordPlus | ELEVATION MYOCARDIAL-INFARCTION | - |
dc.subject.keywordPlus | OPTICAL COHERENCE TOMOGRAPHY | - |
dc.subject.keywordPlus | TERM-FOLLOW-UP | - |
dc.subject.keywordPlus | BALLOON DILATION | - |
dc.subject.keywordPlus | ENDEAVOR-III | - |
dc.subject.keywordPlus | MALAPPOSITION | - |
dc.subject.keywordPlus | APPOSITION | - |
dc.subject.keywordPlus | THROMBOSIS | - |
dc.subject.keywordPlus | INTERVENTION | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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