Role of FDG-PET/CT in detecting lymphomatous bone marrow involvement in patients with newly diagnosed diffuse large B-cell lymphoma
DC Field | Value | Language |
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dc.contributor.author | Hong, Junshik | - |
dc.contributor.author | Lee, Yukyung | - |
dc.contributor.author | Park, Yeonjeong | - |
dc.contributor.author | Kim, Seog Gyun | - |
dc.contributor.author | Hwang, Kyung Hoon | - |
dc.contributor.author | Park, Soon Ho | - |
dc.contributor.author | Jeong, Jihoon | - |
dc.contributor.author | Kim, Kyung-Hee | - |
dc.contributor.author | Ahn, Jeong Yeal | - |
dc.contributor.author | Park, Sanghui | - |
dc.contributor.author | Park, Jinny | - |
dc.contributor.author | Lee, Jae Hoon | - |
dc.date.available | 2020-02-29T06:41:57Z | - |
dc.date.created | 2020-02-05 | - |
dc.date.issued | 2012-05 | - |
dc.identifier.issn | 0939-5555 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/16431 | - |
dc.description.abstract | To evaluate the role of FDG-PET/CT in detecting bone marrow (BM) involvement, pre-treatment bilateral bone marrow biopsies (BMBs) and FDG-PET/CT scans of 89 patients with diffuse large B-cell lymphoma (DLBCL) treated with rituximab-CHOP were reviewed and analyzed. Fourteen patients (15.7%) had lymphomatous involvement based on BMB (BMB+), and 17 patients (19.1%) had the possibility of BM involvement on FDG-PET/CT (FDG-PET/CT+). Seventy-two patients (80.8%) had concordant results between BMB and FDG-PET/CT (seven patients were positive for both, and 65 patients were negative for both), but 17 patients (19.2%) had a discordant interpretation (seven patients were BMB+ and FDG-PET/CT-, and ten were BMB- and FDG-PET/CT+). Although BMB+ patients had an inferior 2-year EFS (37.0% vs. 79.8%, p < 0.001) and OS (36.3% vs. 81.0%, p < 0.001) compared to BMB- patients, no differences in EFS (62.6% vs. 72.7%, p = 0.185) and OS (59.4% vs. 78.0%, p = 0.146) were shown between FDG-PET/CT+ and FDG-PET/CT- patients. Whereas six of seven patients with diffuse hypermetabolism were BMB+, only one of ten patients with focal hypermetabolism was BMB+. The results suggest that FDG-PET/CT had a limited value to detect BM involvement in patients with DLBCL. Focal hypermetabolism of hematopoietic BM in FDG-PET/CT had no impact on survival. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER | - |
dc.relation.isPartOf | ANNALS OF HEMATOLOGY | - |
dc.subject | NON-HODGKINS-LYMPHOMA | - |
dc.subject | INTERNATIONAL WORKSHOP | - |
dc.subject | MALIGNANT-LYMPHOMA | - |
dc.subject | RESPONSE CRITERIA | - |
dc.subject | DISEASE | - |
dc.subject | CLASSIFICATION | - |
dc.subject | INFILTRATION | - |
dc.subject | MANAGEMENT | - |
dc.subject | COMMITTEE | - |
dc.subject | UTILITY | - |
dc.title | Role of FDG-PET/CT in detecting lymphomatous bone marrow involvement in patients with newly diagnosed diffuse large B-cell lymphoma | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000302473100004 | - |
dc.identifier.doi | 10.1007/s00277-011-1353-6 | - |
dc.identifier.bibliographicCitation | ANNALS OF HEMATOLOGY, v.91, no.5, pp.687 - 695 | - |
dc.identifier.scopusid | 2-s2.0-84861471316 | - |
dc.citation.endPage | 695 | - |
dc.citation.startPage | 687 | - |
dc.citation.title | ANNALS OF HEMATOLOGY | - |
dc.citation.volume | 91 | - |
dc.citation.number | 5 | - |
dc.contributor.affiliatedAuthor | Hong, Junshik | - |
dc.contributor.affiliatedAuthor | Lee, Yukyung | - |
dc.contributor.affiliatedAuthor | Park, Yeonjeong | - |
dc.contributor.affiliatedAuthor | Kim, Seog Gyun | - |
dc.contributor.affiliatedAuthor | Hwang, Kyung Hoon | - |
dc.contributor.affiliatedAuthor | Park, Soon Ho | - |
dc.contributor.affiliatedAuthor | Jeong, Jihoon | - |
dc.contributor.affiliatedAuthor | Kim, Kyung-Hee | - |
dc.contributor.affiliatedAuthor | Ahn, Jeong Yeal | - |
dc.contributor.affiliatedAuthor | Park, Sanghui | - |
dc.contributor.affiliatedAuthor | Park, Jinny | - |
dc.contributor.affiliatedAuthor | Lee, Jae Hoon | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Lymphoma | - |
dc.subject.keywordAuthor | FDG-PET/CT | - |
dc.subject.keywordAuthor | Bone marrow | - |
dc.subject.keywordAuthor | Diffuse large B-cell lymphoma | - |
dc.subject.keywordPlus | NON-HODGKINS-LYMPHOMA | - |
dc.subject.keywordPlus | INTERNATIONAL WORKSHOP | - |
dc.subject.keywordPlus | MALIGNANT-LYMPHOMA | - |
dc.subject.keywordPlus | RESPONSE CRITERIA | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | CLASSIFICATION | - |
dc.subject.keywordPlus | INFILTRATION | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | COMMITTEE | - |
dc.subject.keywordPlus | UTILITY | - |
dc.relation.journalResearchArea | Hematology | - |
dc.relation.journalWebOfScienceCategory | Hematology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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