Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration in Association With CADASIL
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Hee-Jin | - |
dc.contributor.author | Kim, Hyun Young | - |
dc.contributor.author | Paek, Won Ki | - |
dc.contributor.author | Park, Aram | - |
dc.contributor.author | Park, Mee Young | - |
dc.contributor.author | Ki, Chang Seok | - |
dc.contributor.author | Park, Hyeon-Mi | - |
dc.contributor.author | Kim, Seung H. | - |
dc.date.available | 2020-02-29T06:44:50Z | - |
dc.date.created | 2020-02-05 | - |
dc.date.issued | 2012-03 | - |
dc.identifier.issn | 1074-7931 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/16548 | - |
dc.description.abstract | Amyotrophic lateral sclerosis (ALS) can present with heterogeneous symptoms resulting from the involvement of multiple brain systems including extramotor cortical areas. Involvement of other brain areas can cause diverse clinical symptoms including cognitive impairment and extrapyramidal symptoms. We report the case of a 50-year-old woman with bulbar onset ALS and frontotemporal lobar degeneration (FTLD), confirmed as cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). The patient and her first-degree relatives harbored a mutation (R75P) in the NOTCH3 gene, indicative of vascular deficits. The details of this case add plausibility to the idea that ALS, FTLD, and CADASIL are different aspects of a spectrum of disorders with overlapping pathologic mechanisms. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.relation.isPartOf | NEUROLOGIST | - |
dc.subject | MOTOR-NEURON DISEASE | - |
dc.subject | ALS | - |
dc.subject | NEURODEGENERATION | - |
dc.subject | DYSFUNCTION | - |
dc.subject | CRITERIA | - |
dc.subject | TDP-43 | - |
dc.title | Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration in Association With CADASIL | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000300908200011 | - |
dc.identifier.doi | 10.1097/NRL.0b013e318247bb2d | - |
dc.identifier.bibliographicCitation | NEUROLOGIST, v.18, no.2, pp.92 - 95 | - |
dc.identifier.scopusid | 2-s2.0-84863248570 | - |
dc.citation.endPage | 95 | - |
dc.citation.startPage | 92 | - |
dc.citation.title | NEUROLOGIST | - |
dc.citation.volume | 18 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | Park, Hyeon-Mi | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | amyotrophic lateral sclerosis | - |
dc.subject.keywordAuthor | frontotemporal lobar degeneration | - |
dc.subject.keywordAuthor | CADASIL | - |
dc.subject.keywordPlus | MOTOR-NEURON DISEASE | - |
dc.subject.keywordPlus | ALS | - |
dc.subject.keywordPlus | NEURODEGENERATION | - |
dc.subject.keywordPlus | DYSFUNCTION | - |
dc.subject.keywordPlus | CRITERIA | - |
dc.subject.keywordPlus | TDP-43 | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.