A Case of B-cell Lymphoma, Unclassifiable, with Features Intermediate between Diffuse Large B-cell Lymphoma and Burkitt Lymphoma in a Korean Child
DC Field | Value | Language |
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dc.contributor.author | Ahn, Jeong Yeal | - |
dc.contributor.author | Seo, Yiel Hea | - |
dc.contributor.author | Park, Pil Whan | - |
dc.contributor.author | Kim, Kyung Hee | - |
dc.contributor.author | Park, Mi Jung | - |
dc.contributor.author | Jeong, Ji Hoon | - |
dc.contributor.author | Park, Soon Ho | - |
dc.contributor.author | Song, Young Hee | - |
dc.date.available | 2020-02-29T06:44:58Z | - |
dc.date.created | 2020-02-05 | - |
dc.date.issued | 2012-03 | - |
dc.identifier.issn | 2234-3806 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/16555 | - |
dc.description.abstract | B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma (BL) (intermediate DLBCL/BL), is a heterogeneous group with some features resembling DLBCL and others resembling BL. Here, we report a case of intermediate DLBCL/BL in a Korean child. A 2-yr-old male was admitted for evaluation and management of left hip pain. Immunohistochemistry of a biopsy of the femur neck revealed tumor cells positive for CD20, CD10, BCL2, BCL6, and Ki67. A bone marrow (BM) aspirate smear revealed that 49.3% of all nucleated cells were abnormal lymphoid cells, composed of large- and medium-sized cells. Immunophenotyping of the neoplastic cells revealed positivity for CD19, CD10, CD20, and slg lambda and negativity for CD34, Tdt, and myeloperoxidase (MPO). Cytogenetic and FISH analyses showed a complex karyotype, including t(8;14)(q24.1;q32) and IGH-MYC fusion. Intensive chemotherapy was initiated, including prednisone, vincristine, L-asparaginase, daunorubicin, and central nervous system prophylaxis with intrathecal methotrexate (MTX) and cytarabine. One month after the initial diagnosis, BM examination revealed the persistent of abnormal lymphoid cells; cerebrospinal fluid cytology, including cytospin, showed atypical lymphoid cells. The patient was treated again with cyclophosphamide, vincristine, prednisone, adriamycin, MTX, and intrathecal MTX and cytarabine. The patient died of sepsis 5 months after the second round of chemotherapy. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC LABORATORY MEDICINE | - |
dc.relation.isPartOf | ANNALS OF LABORATORY MEDICINE | - |
dc.title | A Case of B-cell Lymphoma, Unclassifiable, with Features Intermediate between Diffuse Large B-cell Lymphoma and Burkitt Lymphoma in a Korean Child | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000301682500011 | - |
dc.identifier.doi | 10.3343/alm.2012.32.2.162 | - |
dc.identifier.bibliographicCitation | ANNALS OF LABORATORY MEDICINE, v.32, no.2, pp.162 - 166 | - |
dc.identifier.kciid | ART001639988 | - |
dc.identifier.scopusid | 2-s2.0-84859166250 | - |
dc.citation.endPage | 166 | - |
dc.citation.startPage | 162 | - |
dc.citation.title | ANNALS OF LABORATORY MEDICINE | - |
dc.citation.volume | 32 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | Ahn, Jeong Yeal | - |
dc.contributor.affiliatedAuthor | Seo, Yiel Hea | - |
dc.contributor.affiliatedAuthor | Park, Pil Whan | - |
dc.contributor.affiliatedAuthor | Kim, Kyung Hee | - |
dc.contributor.affiliatedAuthor | Park, Mi Jung | - |
dc.contributor.affiliatedAuthor | Jeong, Ji Hoon | - |
dc.contributor.affiliatedAuthor | Park, Soon Ho | - |
dc.contributor.affiliatedAuthor | Song, Young Hee | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Diffuse large B-cell lymphoma | - |
dc.subject.keywordAuthor | Burkitt lymphoma | - |
dc.subject.keywordAuthor | Gray zone lymphoma | - |
dc.relation.journalResearchArea | Medical Laboratory Technology | - |
dc.relation.journalWebOfScienceCategory | Medical Laboratory Technology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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