Immunostimulatory effects of gold nanorod and silica-coated gold nanorod on RAW 264.7 mouse macrophages
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Ji Young | - |
dc.contributor.author | Park, Wansu | - |
dc.contributor.author | Yi, Dong Kee | - |
dc.date.available | 2020-02-29T06:45:36Z | - |
dc.date.created | 2020-02-05 | - |
dc.date.issued | 2012-02-25 | - |
dc.identifier.issn | 0378-4274 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/16576 | - |
dc.description.abstract | In this study, we have investigated immunostimulatory effects of gold nanorod (Au) and silica-coated gold nanorod (SiAu) concerned with inflammatory mediators such as calcium (Ca), hydrogen peroxide, nitric oxide (NO), various cytokines, prostaglandin E2 (PGE2), transcription factors, and immune response gene in RAW 264.7 mouse macrophages. Both Au and SiAu significantly increased the release of Ca, hydrogen peroxide, NO, IL-1 alpha, IL-1 beta, IL-6, IL-10, IP-10, MCP-1, MCP-3, INF-alpha, RANTES, G-CSF, GM-CSF, LIF, MIP-2, VEGF, and PGE2 with enhancing expression of STAT1, STAT3, c-Fos, and COX-2 mRNA in RAW 264.7 cells. The results suggest that Au and SiAu have immunostimulatory properties to strengthen immune reactions via calcium-transcription factors pathway in macrophage. (C) 2011 Elsevier Ireland Ltd. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER IRELAND LTD | - |
dc.relation.isPartOf | TOXICOLOGY LETTERS | - |
dc.subject | PHOTOTHERMAL THERAPY | - |
dc.subject | BACTERIAL-ENDOTOXIN | - |
dc.subject | WATER EXTRACT | - |
dc.subject | NANOPARTICLES | - |
dc.subject | NANOCOMPOSITES | - |
dc.subject | MECHANISMS | - |
dc.subject | RELEASE | - |
dc.subject | CANCER | - |
dc.subject | CELLS | - |
dc.subject | TNF | - |
dc.title | Immunostimulatory effects of gold nanorod and silica-coated gold nanorod on RAW 264.7 mouse macrophages | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000300268700007 | - |
dc.identifier.doi | 10.1016/j.toxlet.2011.11.024 | - |
dc.identifier.bibliographicCitation | TOXICOLOGY LETTERS, v.209, no.1, pp.51 - 57 | - |
dc.identifier.scopusid | 2-s2.0-84155176932 | - |
dc.citation.endPage | 57 | - |
dc.citation.startPage | 51 | - |
dc.citation.title | TOXICOLOGY LETTERS | - |
dc.citation.volume | 209 | - |
dc.citation.number | 1 | - |
dc.contributor.affiliatedAuthor | Lee, Ji Young | - |
dc.contributor.affiliatedAuthor | Park, Wansu | - |
dc.contributor.affiliatedAuthor | Yi, Dong Kee | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Gold nanorod | - |
dc.subject.keywordAuthor | Silica-coated gold nanorod | - |
dc.subject.keywordAuthor | Immunostimulatory | - |
dc.subject.keywordAuthor | Macrophage | - |
dc.subject.keywordAuthor | Cytokine | - |
dc.subject.keywordPlus | PHOTOTHERMAL THERAPY | - |
dc.subject.keywordPlus | BACTERIAL-ENDOTOXIN | - |
dc.subject.keywordPlus | WATER EXTRACT | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | NANOCOMPOSITES | - |
dc.subject.keywordPlus | MECHANISMS | - |
dc.subject.keywordPlus | RELEASE | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | TNF | - |
dc.relation.journalResearchArea | Toxicology | - |
dc.relation.journalWebOfScienceCategory | Toxicology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.