Generation of Mouse Basal Ganglia Diffusion Tractography Using 9.4T MRI
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Shim, Jae-Hyuk | - |
dc.contributor.author | Im, Sang-Jin | - |
dc.contributor.author | Kim, A-Yoon | - |
dc.contributor.author | Kim, Yong-Tae | - |
dc.contributor.author | Kim, Eun Bee | - |
dc.contributor.author | Baek, Hyeon-Man | - |
dc.date.available | 2020-02-27T03:42:47Z | - |
dc.date.created | 2020-02-04 | - |
dc.date.issued | 2019-04 | - |
dc.identifier.issn | 1226-2560 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/1670 | - |
dc.description.abstract | Over the years, diffusion tractography has seen increasing use for comparing minute differences in connectivity of brain structures in neurodegenerative diseases and treatments. Studies on connectivity between basal ganglia has been a focal point for studying the effects of diseases such as Parkinson's and Alzheimer's, as well as the effects of treatments such as deep brain stimulation. Additionally, in previous studies, diffusion tractography was utilized in disease mouse models to identify white matter alterations, as well as biomarkers that occur in the progression of disease. However, despite the extensive use of mouse models to study model diseases,the structural connectivity of the mouse basal ganglia has been inadequately explored. In this study, we present the methodology of segmenting the basal ganglia of a mouse brain, then generating diffusion tractography between the segmented basal ganglia structures. Additionally, we compare the relative levels of connectivity of connecting fibers between each basal ganglia structure, as well as visualize the shapes of each connection. We believe that our results and future studies utilizing diffusion tractography will be beneficial for properly assessing some of the connectivity changes that arc found in the basal ganglia of various mouse models. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC BRAIN & NEURAL SCIENCE, KOREAN SOC NEURODEGENERATIVE DISEASE | - |
dc.relation.isPartOf | EXPERIMENTAL NEUROBIOLOGY | - |
dc.subject | SUBTHALAMIC NUCLEUS | - |
dc.subject | PARKINSONS-DISEASE | - |
dc.subject | ALZHEIMERS-DISEASE | - |
dc.subject | ANIMAL-MODELS | - |
dc.subject | BRAIN | - |
dc.subject | DOPAMINE | - |
dc.subject | PATTERNS | - |
dc.subject | CONNECTIVITY | - |
dc.subject | CONNECTOME | - |
dc.subject | PATHOLOGY | - |
dc.title | Generation of Mouse Basal Ganglia Diffusion Tractography Using 9.4T MRI | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000468151200013 | - |
dc.identifier.doi | 10.5607/en.2019.28.2.300 | - |
dc.identifier.bibliographicCitation | EXPERIMENTAL NEUROBIOLOGY, v.28, no.2, pp.300 - 310 | - |
dc.identifier.kciid | ART002464337 | - |
dc.identifier.scopusid | 2-s2.0-85066885384 | - |
dc.citation.endPage | 310 | - |
dc.citation.startPage | 300 | - |
dc.citation.title | EXPERIMENTAL NEUROBIOLOGY | - |
dc.citation.volume | 28 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | Shim, Jae-Hyuk | - |
dc.contributor.affiliatedAuthor | Im, Sang-Jin | - |
dc.contributor.affiliatedAuthor | Kim, A-Yoon | - |
dc.contributor.affiliatedAuthor | Kim, Yong-Tae | - |
dc.contributor.affiliatedAuthor | Kim, Eun Bee | - |
dc.contributor.affiliatedAuthor | Baek, Hyeon-Man | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Mouse | - |
dc.subject.keywordAuthor | Basal Ganglia | - |
dc.subject.keywordAuthor | MRI | - |
dc.subject.keywordAuthor | Diffusion tractography | - |
dc.subject.keywordPlus | SUBTHALAMIC NUCLEUS | - |
dc.subject.keywordPlus | PARKINSONS-DISEASE | - |
dc.subject.keywordPlus | ALZHEIMERS-DISEASE | - |
dc.subject.keywordPlus | ANIMAL-MODELS | - |
dc.subject.keywordPlus | BRAIN | - |
dc.subject.keywordPlus | DOPAMINE | - |
dc.subject.keywordPlus | PATTERNS | - |
dc.subject.keywordPlus | CONNECTIVITY | - |
dc.subject.keywordPlus | CONNECTOME | - |
dc.subject.keywordPlus | PATHOLOGY | - |
dc.relation.journalResearchArea | Research & Experimental Medicine | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Medicine, Research & Experimental | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.