Influence of Midazolam and Glycopyrrolate on Intra-operative Body Temperature in Abdominal Surgical Patients
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김은주 | - |
dc.contributor.author | 윤혜상 | - |
dc.date.available | 2020-02-29T07:44:10Z | - |
dc.date.created | 2020-02-12 | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 2383-6415 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/16850 | - |
dc.description.abstract | Purpose: Influence of benzodiazepine (midazolam)or cholinergic inhibitor (atropine or glycopyrrlate) on intra-operative body temperature remains unclear and controversial. This study compares intra-operative body temperature in 50 abdominal surgical patients under general anesthesia between the administration of midazolam and glycopyrrolate in combination, or glycopyrrolate alone. Methods: Patients who underwent abdominal surgery were recruited from September 2008 through October 2009 at Gachon University Gil hospital in Incheon. Core body temperature was measured in the right ear using a tympanic membrane thermometer at induction of general anesthesia and at 1 hr, 2 hr, and 3 hr after induction. Results: There were no differences in core body temperature at any measurement point between either patient group (F=1.08, p=.377). Core body temperature decreased throughout the 3 hr after induction in both groups (F=9.22, p<.001). Specially, core temperatures at induction of general anesthesia (p<.001), 1 hr (p<.001), 2 hr (p<.001), and 3 hr (p<.001) after induction were lower than before administration of midazolam and glycopyrrolate, or glycopyrrolate alone. Conclusion: We conclude that a cholinergic inhibitor (glycopyrrolate, 0.1 mg) therefore seems not to affect intra-operative body temperature of patients given a benzodiazepine (midazolam, 0.04 mg kg-1), and not to increase body temperature in patients not given a benzodiazepine during the 3 hr after the induction of general anesthesia. Intra-operative warming therefore is needed to prevent hypothermia in surgical patients who receive pre-operative administration of midazolam and/or glycopyrrolate. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | 기초간호학회 | - |
dc.relation.isPartOf | Journal of korean biological nursing science | - |
dc.title | Influence of Midazolam and Glycopyrrolate on Intra-operative Body Temperature in Abdominal Surgical Patients | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 2 | - |
dc.identifier.bibliographicCitation | Journal of korean biological nursing science, v.14, no.1, pp.25 - 32 | - |
dc.identifier.kciid | ART001659102 | - |
dc.citation.endPage | 32 | - |
dc.citation.startPage | 25 | - |
dc.citation.title | Journal of korean biological nursing science | - |
dc.citation.volume | 14 | - |
dc.citation.number | 1 | - |
dc.contributor.affiliatedAuthor | 김은주 | - |
dc.contributor.affiliatedAuthor | 윤혜상 | - |
dc.subject.keywordAuthor | Glycopyrrolate | - |
dc.subject.keywordAuthor | Hypothermia | - |
dc.subject.keywordAuthor | Intra-operative care | - |
dc.subject.keywordAuthor | Midazolam | - |
dc.description.journalRegisteredClass | kci | - |
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