한국약용식물의 최종당화산물 생성저해활성 검색(VII)

Abstract

In this study, 49 Korean herbal medicines have been investigated with an in vitro evaluation system using glycation end products (AGEs) formation inhibitory activity. Of these, 18 herbal medicines (IC_50<50 µg/ml) were found to have significant AGEs formation inhibitory activity. Of these, five herbal medicines (IC_50<10 µg/ml) were found to have significant AGEs formation inhibitory activity. Particularly, Mallotus japonicus (twigs and leaves), Rhus javanica (twigs and leaves), Boehmeria nivea (whole plants), Quercus acuta (stems), and Eurya japonica (stems) showed more potent inhibitory activity (approximately 9-37 fold) than the positive control aminoguanidine (IC_50=76.47 µg/ml).