A Case of Balsalazide-Induced Limited Form of Granulomatosis with Polyangiitis with Bronchiolitis Obliterans Organizing Pneumonia-like Variant in Ulcerative Colitis
- Authors
- Kang, Shin Myung; Jang, Young Rock; Yoon, Hyun-Hwa; Kim, Suji; Kim, Eun Young; Ha, Seung Yeon; Park, Jeong-Woong
- Issue Date
- Mar-2012
- Publisher
- 대한결핵및호흡기학회
- Keywords
- Balsalazide; Colitis; Ulcerative; Wegener granulomatosis
- Citation
- Tuberculosis and Respiratory Diseases, v.72, no.3, pp.323 - 327
- Journal Title
- Tuberculosis and Respiratory Diseases
- Volume
- 72
- Number
- 3
- Start Page
- 323
- End Page
- 327
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/17442
- DOI
- 10.4046/trd.2012.72.3.323
- ISSN
- 1738-3536
- Abstract
- 5-Aminosalicylate agents are the main therapeutic agents for ulcerative colitis. Balsalazide is a prodrug of 5-aminosalicylate and has fewer side effects than the other 5-aminosalicylate agents. Pulmonary complications resembling granulomatosis with polyangiitis in ulcerative colitis are extremely rare. Here, we report a patient with ulcerative colitis on balsalazide presenting respiratory symptoms and multiple pulmonary nodules from a chest radiography that was pathologically diagnosed with a limited form of granulomatosis with polyangiitis with bronchiolitis obliterans organizing pneumonia-like variant. To our knowledge, this is the first report of a balsalazide-induced limited form of granulomatosis with polyangiitis with bronchiolitis obliterans organizing pneumonia-like variant. Copyright©2012. The Korean Academy of Tuberculosis and Respiratory Diseases. All rights reserved.
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