Protective field efficacy study of influenza vaccines for korean children and adolescent in 2010-2011 season한국의 소아 청소년에서 인플루엔자 백신의 효능평가
- Other Titles
- 한국의 소아 청소년에서 인플루엔자 백신의 효능평가
- Authors
- Kim, S.Y.; Kim, N.H.; Eun, B.W.; Kim, S.H.; Park, K.W.; Jang, H.O.; Kang, E.K.; Kim, D.H.
- Issue Date
- Dec-2012
- Publisher
- 대한소아감염학회
- Keywords
- Field efficacy; Influenza vaccine
- Citation
- Korean Journal of Pediatric Infectious Diseases, v.19, no.3, pp.149 - 156
- Journal Title
- Korean Journal of Pediatric Infectious Diseases
- Volume
- 19
- Number
- 3
- Start Page
- 149
- End Page
- 156
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/17494
- ISSN
- 1226-3923
- Abstract
- Purpose : We conducted a prospective comparative clinical study to determine the field efficacy of the 2010-2011 influenza vaccines [Influenza virus strains; A/California/7/2009 (H1N1), A/Perth/16/2009 (H3N2), B/Brisbane/60/2008] in healthy Korean children under 18 years of age. Methods : In this study, we enrolled subjects aged between 6 months and 18 years and divided them into 2 study groups: a group who received the influenza vaccines (407 subjects), and a control group who did not receive the influenza vaccines (230 subjects). Ours was a multicenter study that involved 7 hospitals, including the Korea Cancer Center Hospital. The study was conducted between September 2010 and February 2011. We collected nasal wash or throat swab samples from subjects who presented with acute febrile respiratory or influenza-like illnesses at the hospital. We used PCR to confirm the presence of the influenza virus in the respiratory samples and characterize the virus type. Results : In this study, we collected 22 respiratory samples from the influenza-vaccinated group and found 3 cases of influenza virus infection. Similarly, we collected 21 samples from the control group and found 12 cases of influenza virus infection among 10 subjects during the study period. We determined the field efficacy of the 2010-2011 seasonal influenza vaccines to be 83.2% in healthy Korean children and adolescents. Conclusion : In this study, we determined the field efficacy of the 2010-2011 seasonal influenza vaccines in healthy Korean children and adolescents. We found that the field efficacy of 2010-2011 seasonal influenza vaccines was adequate. Copyright © Korean J Pediatr Infect Dis. 2012.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - ETC > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/17494)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.