Usefulness of 18 F-FDG PET/CT for the evaluation of bone marrow involvement in patients with high-grade non-Hodgkin's lymphoma
DC Field | Value | Language |
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dc.contributor.author | Lee, Y. | - |
dc.contributor.author | Hwang, K.H. | - |
dc.contributor.author | Hong, J. | - |
dc.contributor.author | Park, J. | - |
dc.contributor.author | Lee, J.H. | - |
dc.contributor.author | Ahn, J.Y. | - |
dc.contributor.author | Kim, J.H. | - |
dc.contributor.author | Lee, H. | - |
dc.contributor.author | Kim, S.G. | - |
dc.contributor.author | Shin, J.Y. | - |
dc.date.available | 2020-02-29T09:45:36Z | - |
dc.date.created | 2020-02-11 | - |
dc.date.issued | 2012-12 | - |
dc.identifier.issn | 1869-3474 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/17511 | - |
dc.description.abstract | Purpose To assess the usefulness of 18 F-fluorodeoxyglucose PET/CT in the detection of bone marrow (BM) involvement of high-grade non-Hodgkin's lymphoma (NHL). Methods One hundred twenty patients with newly diagnosed diffuse large B-cell lymphoma or peripheral T-cell lymphoma between January 2007 and June 2011, who received BM trephine biopsy and 18 F-FDG PET/CT before chemotherapy, were included in this retrospective study. We reviewed their 18 F-FDG PET/CT images and bone marrow biopsy (BMB) results. After reviewing the images, we reviewed the medical records and radiological findings of interesting patients. Results There were 23 18 F-FDG PET/CT scans in which the marrow was considered to be abnormal (either positive or equivocal), and 97 18 F-FDG PET/CT scans were regarded as having negative FDG uptake. Of 120 patients, 100 (83.3 %) had a concordant result of BM interpretation between 18 FFDG PET/CT and BMB, and the remaining 20 patients had discordant results. Among 23 patients with either positive or equivocal 18 F-FDG PET/CT scans, 1 of 12 patients with 'positive' 18 F-FDG PET/CT had a lymphomatous involvement on BMB. In contrast, 10 of 11 patients with 'equivocal' BM hypermetabolism were reported as having positive involvement by BMB. Patients with abnormal 18 F-FDG PET/CT had significantly higher mSUVhighest than those with normal FDG-PET/CT. Conclusions 18 -FDG PET/CTand BMB are complementary techniques in assessing the presence of BM involvement in patients with high-grade NHL. The increasing availability of 18 F-FDG PET/CTwill raise the need for additional biopsy for FDG-avid lesions, especially in patients with negative standard BMBs. 18 F-FDG PET/CT can be useful as a decisionmaking tool for determining whether to perform a standard BMB or targeted biopsy to the FDG-avid lesion as an initial staging procedure.A direct bone biopsy for FDGpositive bone lesions should be included in staging guidelines in future. In 18 F-FDG PET/CT-negative cases, BMB is still a powerful procedure, but BMB alone is insufficient for full evaluation of BM. © Korean Society of Nuclear Medicine 2012. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | 대한핵의학회 | - |
dc.relation.isPartOf | Nuclear Medicine and Molecular Imaging | - |
dc.title | Usefulness of 18 F-FDG PET/CT for the evaluation of bone marrow involvement in patients with high-grade non-Hodgkin's lymphoma | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.doi | 10.1007/s13139-012-0153-9 | - |
dc.identifier.bibliographicCitation | Nuclear Medicine and Molecular Imaging, v.46, no.4, pp.269 - 277 | - |
dc.identifier.kciid | ART001718928 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-84875432018 | - |
dc.citation.endPage | 277 | - |
dc.citation.startPage | 269 | - |
dc.citation.title | Nuclear Medicine and Molecular Imaging | - |
dc.citation.volume | 46 | - |
dc.citation.number | 4 | - |
dc.contributor.affiliatedAuthor | Lee, Y. | - |
dc.contributor.affiliatedAuthor | Hwang, K.H. | - |
dc.contributor.affiliatedAuthor | Hong, J. | - |
dc.contributor.affiliatedAuthor | Park, J. | - |
dc.contributor.affiliatedAuthor | Lee, J.H. | - |
dc.contributor.affiliatedAuthor | Ahn, J.Y. | - |
dc.contributor.affiliatedAuthor | Kim, J.H. | - |
dc.contributor.affiliatedAuthor | Lee, H. | - |
dc.contributor.affiliatedAuthor | Kim, S.G. | - |
dc.contributor.affiliatedAuthor | Shin, J.Y. | - |
dc.type.docType | Review | - |
dc.subject.keywordAuthor | 18 F-FDG PET/CT | - |
dc.subject.keywordAuthor | Bone marrow | - |
dc.subject.keywordAuthor | Lymphoma | - |
dc.subject.keywordPlus | cyclophosphamide | - |
dc.subject.keywordPlus | doxorubicin | - |
dc.subject.keywordPlus | fluorodeoxyglucose f 18 | - |
dc.subject.keywordPlus | prednisone | - |
dc.subject.keywordPlus | rituximab | - |
dc.subject.keywordPlus | vincristine | - |
dc.subject.keywordPlus | adult | - |
dc.subject.keywordPlus | aged | - |
dc.subject.keywordPlus | bone lesion | - |
dc.subject.keywordPlus | bone marrow biopsy | - |
dc.subject.keywordPlus | bone marrow disease | - |
dc.subject.keywordPlus | cancer grading | - |
dc.subject.keywordPlus | computed tomography scanner | - |
dc.subject.keywordPlus | computer assisted tomography | - |
dc.subject.keywordPlus | diagnostic imaging equipment | - |
dc.subject.keywordPlus | female | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | large cell lymphoma | - |
dc.subject.keywordPlus | major clinical study | - |
dc.subject.keywordPlus | male | - |
dc.subject.keywordPlus | medical record review | - |
dc.subject.keywordPlus | nonhodgkin lymphoma | - |
dc.subject.keywordPlus | peripheral T cell lymphoma | - |
dc.subject.keywordPlus | positron emission tomography | - |
dc.subject.keywordPlus | positron emission tomography scanner | - |
dc.subject.keywordPlus | priority journal | - |
dc.subject.keywordPlus | retrospective study | - |
dc.subject.keywordPlus | review | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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